Caccia M R, Mangoni A
J Neurol. 1985;232(1):55-7. doi: 10.1007/BF00314043.
The authors present ten cases of essential tremor, studied before and after administration of clonidine with clinical tests and electrophysiological recordings. Improvement due to the desynchronizing effect of clonidine on tremor was observed in all cases. Possible mechanisms acting on the central and peripheral nervous system are discussed.
作者报告了10例特发性震颤病例,在给予可乐定前后进行了临床测试和电生理记录研究。在所有病例中均观察到由于可乐定对震颤的去同步化作用而导致的改善。文中讨论了作用于中枢和外周神经系统的可能机制。