Pari Rizfi Fariz, Uju Uju, Hardiningtyas Safrina Dyah, Ramadhan Wahyu, Wakabayashi Rie, Goto Masahiro, Kamiya Noriho
Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, 744 Motooka, Fukuoka 819-0395, Japan.
Department of Aquatic Product Technology, Faculty of Fisheries and Marine Sciences, IPB University, Bogor 16680, Indonesia.
Mar Drugs. 2025 Jan 24;23(2):56. doi: 10.3390/md23020056.
Green seaweed is currently underused compared with other major seaweed types. Many scientists have reported applications of the green seaweed in various fields in recent years, which makes it a candidate for biomass production in industrial biorefineries. contains a unique polysaccharide called ulvan, which is being considered for medicinal and pharmacological applications. Ulvan is a sulfated polysaccharide including rhamnose and glucuronic acid residues, which has a range of bioactivities, including immunomodulatory, antimicrobial, and anticoagulant properties. The biocompatibility of ulvan makes it a versatile candidate for biomaterial design. This review presents an in-depth analysis of the potential applications of ulvan, starting with extraction methods and structural/biological characterization and moving on to biomaterial design. We also highlight the advantages of ulvan over traditional seaweed polysaccharides such as agar, carrageenan, and alginate.
与其他主要类型的海藻相比，绿藻目前未得到充分利用。近年来，许多科学家报道了绿藻在各个领域的应用，这使其成为工业生物炼制中生物质生产的一个候选对象。绿藻含有一种名为岩藻聚糖硫酸酯的独特多糖，正被考虑用于医学和药理学应用。岩藻聚糖硫酸酯是一种含有鼠李糖和葡萄糖醛酸残基的硫酸化多糖，具有一系列生物活性，包括免疫调节、抗菌和抗凝血特性。岩藻聚糖硫酸酯的生物相容性使其成为生物材料设计的一个通用候选对象。本综述对岩藻聚糖硫酸酯的潜在应用进行了深入分析，从提取方法和结构/生物学表征开始，进而探讨生物材料设计。我们还强调了岩藻聚糖硫酸酯相对于传统海藻多糖如琼脂、卡拉胶和藻酸盐的优势。
