Forrester R L, Worrall J, Robertson W R, Wataji L J, Wilhelm D
Ther Drug Monit. 1979;1(3):381-5. doi: 10.1097/00007691-197901030-00011.
The homogeneous enzyme immunoassay (EMIT) and radioimmunoassay (RIA) procedures for the quantitation of theophylline concentrations in serum were evaluated and compared. Both methods exhibited curves linear over the therapeutic range (range of concentration, 2.0-33.0 microgram/ml). Precision was acceptable for both methods with the coefficient of variation being less than 8.3%. The RIA procedure was found to be slightly more precise. The correlations between the EMIT and RIA procedures was found to be sufficient to allow the procedures to be used interchangeably. This would facilitate the test availability on a 24 hr, 7 day basis.
对用于定量血清中茶碱浓度的均相酶免疫测定法（EMIT）和放射免疫测定法（RIA）进行了评估和比较。两种方法在治疗范围内（浓度范围为2.0 - 33.0微克/毫升）均呈现线性曲线。两种方法的精密度均可接受，变异系数均小于8.3%。发现RIA方法的精密度略高。EMIT和RIA方法之间的相关性足以允许两种方法互换使用。这将便于在每天24小时、每周7天的基础上进行检测。
