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具有嵌入银纳米颗粒基质的3D打印原位制备水凝胶抗菌伤口贴片。

3D-printed and In-situ prepared hydrogel anti-bacterial wound patch with silver nanoparticle embedded matrix.

作者信息

Amara Hanin, Alam Fahad, El Turk Said, Butt Haider

机构信息

Department of Mechanical & Nuclear Engineering, Khalifa University, Abu Dhabi, United Arab Emirates.

Materials Science and Engineering Department, King Fahd University of Petroleum & Minerals, Dhahran, Saudi Arabia.

出版信息

Heliyon. 2025 Jan 24;11(4):e42186. doi: 10.1016/j.heliyon.2025.e42186. eCollection 2025 Feb 28.

Abstract

The application of wearable hydrogel wound patches has great potential in advancing the field of medicine. However, for high reach and large-scale utilization, the fabrication process of wearable hydrogel wound patches needs to be low-cost, reliable, and have high throughput. Therefore, the incorporation of 3D-printing technology helps in providing a starting point for flexible, high throughput, mechanically enhanced, low-cost, and reliable antibacterial wound patches. 3D-printed patches can perform antibacterial behavior while exhibiting a fast fabrication process in a time range of less than 3 h. The fabricated patch exhibited good water retention, water vapor transmission rates a porosity values indicating that it has a promising potential to be commercialized as a wound patch.

摘要

可穿戴水凝胶伤口贴片的应用在推动医学领域发展方面具有巨大潜力。然而,为了实现广泛应用和大规模使用,可穿戴水凝胶伤口贴片的制造过程需要低成本、可靠且具有高产量。因此,引入3D打印技术有助于为制造灵活、高产量、机械性能增强、低成本且可靠的抗菌伤口贴片提供一个起点。3D打印贴片能够在不到3小时的时间内快速制造出来,同时具备抗菌性能。所制造的贴片表现出良好的保水性、水汽透过率和孔隙率,表明其作为伤口贴片具有商业化的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a243/11867285/3f903c76dc6b/gr1.jpg

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