Jolley S G, Smith E I, Tunell W P
Ann Surg. 1985 Jun;201(6):736-40. doi: 10.1097/00000658-198506000-00010.
Regurgitation and aspiration of feedings is a significant problem in children with impaired oral intake fed via gastrostomy. Using extended (18-24 hour) esophageal pH monitoring to assess gastroesophageal reflux (GER), we studied prospectively 32 children (aged 2 to 16 years) referred for feeding gastrostomy. Twenty-five patients had repeat esophageal pH monitoring after surgery. Prior to surgery, GER was documented in 23 (72%) of the 32 children. Twenty-two of the 23 children with GER before surgery had an antireflux operation performed in conjunction with the feeding gastrostomy. Gastroesophageal reflux was clinically significant in the single failed antireflux operation and in the child with GER before surgery who only had a gastrostomy performed. All nine patients without GER only had gastrostomy performed. Six of these developed GER by pH monitoring after surgery, with significant vomiting in four. Of our 11 patients remaining at risk for GER after surgery, seven (64%) had persistent vomiting with gastrostomy feedings. Thus, 91% (29 of 32) of the children were potentially at risk for GER if a gastrostomy only was performed. We believe these data support the need for a "protective" antireflux operation in children referred for feeding gastrostomy.
对于经胃造口喂养的口腔摄入功能受损儿童,喂养物的反流和误吸是一个重大问题。我们通过延长(18 - 24小时)食管pH监测来评估胃食管反流(GER),对32例因喂养问题行胃造口术的儿童(年龄2至16岁)进行了前瞻性研究。25例患者术后进行了重复食管pH监测。术前,32例儿童中有23例(72%)记录到GER。术前23例有GER的儿童中,22例在进行胃造口术的同时接受了抗反流手术。在单一失败的抗反流手术以及术前仅有胃造口术的GER患儿中,胃食管反流具有临床意义。所有9例无GER的患者仅进行了胃造口术。其中6例术后经pH监测出现GER,4例有明显呕吐。在术后仍有GER风险的11例患者中,7例(64%)胃造口喂养时持续呕吐。因此,如果仅进行胃造口术,91%(32例中的29例)的儿童可能有GER风险。我们认为这些数据支持对因喂养问题行胃造口术的儿童进行“保护性”抗反流手术的必要性。