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石棉水泥工人中的肺癌。一项瑞典队列研究及综述。

Lung cancer among asbestos cement workers. A Swedish cohort study and a review.

作者信息

Ohlson C G, Hogstedt C

出版信息

Br J Ind Med. 1985 Jun;42(6):397-402. doi: 10.1136/oem.42.6.397.

DOI:10.1136/oem.42.6.397
PMID:4005192
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1007497/
Abstract

A cohort study of 1176 Swedish asbestos cement workers did not indicate any asbestos related excess mortality. Possible explanations of the negative outcome are relatively low exposure levels and the predominant use of chrysotile in production. Such a tentative conclusion is supported by a review of five mortality studies of workers exposed to asbestos cement that report considerable differences in relative risks for lung cancer. These differences could be explained by various degrees of cumulative exposure, the amount of amphiboles in the production, and methodological shortcomings. A median exposure of 10-20 fibre-years does not seem to cause an increased risk of lung cancer, particularly when only chrysotile is used.

摘要

一项针对1176名瑞典石棉水泥工人的队列研究未显示出任何与石棉相关的超额死亡率。该阴性结果的可能解释是接触水平相对较低以及生产中主要使用温石棉。对五项石棉水泥接触工人死亡率研究的综述支持了这一初步结论,这些研究报告了肺癌相对风险存在显著差异。这些差异可以通过不同程度的累积接触、生产中角闪石的含量以及方法学缺陷来解释。10 - 20纤维年的中位接触量似乎不会增加肺癌风险,尤其是在仅使用温石棉的情况下。

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本文引用的文献

1
Nature, structure, and properties of asbestos cement dust.石棉水泥粉尘的性质、结构与特性
Br J Ind Med. 1980 Feb;37(1):33-41. doi: 10.1136/oem.37.1.33.
2
Occupational exposure to asbestos: population at risk and projected mortality--1980-2030.职业性接触石棉:高危人群及预计死亡率——1980 - 2030年
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Further follow-up study of workers from an asbestos cement factory.对一家石棉水泥厂工人的进一步随访研究。
Br J Ind Med. 1982 Aug;39(3):273-6. doi: 10.1136/oem.39.3.273.
4
Mortality among long-term employees of an Ontario asbestos-cement factory.安大略省一家石棉水泥厂长期员工的死亡率。
Br J Ind Med. 1983 May;40(2):138-44. doi: 10.1136/oem.40.2.138.
5
Decreased lung function in long-term asbestos cement workers: a cross-sectional study.长期石棉水泥工人肺功能下降:一项横断面研究。
Am J Ind Med. 1984;5(5):359-66. doi: 10.1002/ajim.4700050504.
6
Dust exposure and mortality in an American chrysotile asbestos friction products plant.美国温石棉摩擦制品工厂的粉尘暴露与死亡率
Br J Ind Med. 1984 May;41(2):151-7. doi: 10.1136/oem.41.2.151.
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Mortality of workers manufacturing friction materials using asbestos.使用石棉制造摩擦材料的工人的死亡率。
Br J Ind Med. 1983 Feb;40(1):1-7. doi: 10.1136/oem.40.1.1.
8
Mortality of two groups of women who manufactured gas masks from chrysotile and crocidolite asbestos: a 40-year follow-up.两组使用温石棉和青石棉制造防毒面具的女性的死亡率:40年随访
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Pulmonary function of control and industrially exposed Nigerians in asbestos, textile, and toluene diisocyanate-foam factories.石棉、纺织及甲苯二异氰酸酯泡沫工厂中对照人群及职业暴露的尼日利亚人的肺功能。
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Lancet. 1984 Mar 17;1(8377):611-6. doi: 10.1016/s0140-6736(84)91007-9.