Thomas H F, Benjamin I T, Elwood P C, Sweetnam P M
Br J Ind Med. 1982 Aug;39(3):273-6. doi: 10.1136/oem.39.3.273.
A further follow-up traced 1970 workers employed at an asbestos cement factory for at least six months between 1936 and 1977. At the beginning of this period some crocidolite was used in the factory but by the end of 1936 chrysotile had become the only type of asbestos in use. Only 378 women were employed during the period concerned, and of the 30 who had died, none had a cause of death that is generally associated with exposure to asbestos. The mortality experience of the men was examined separately for all workers, all workers alive after 15 or more years after first exposure, and a smaller group of workers who were employed in 1935-6 and may have been exposed to crocidolite. In none of the three groups was there an appreciably raised standardised mortality ratio (SMR) for the causes of death investigated. These were: all causes, all neoplasms, cancers of the lung and pleura, and cancers of the gastrointestinal tract. An excess of lung cancers noted in the first follow-up study in 1964 was not found in this study. Two pleural mesotheliomas were identified but in both cases the men had worked at the factory before 1936 and therefore had been exposed to crocidolite. No cancers of the larynx were found.
进一步的随访追踪了1936年至1977年间在一家石棉水泥厂工作至少六个月的1970名工人。在这段时期开始时,工厂使用了一些青石棉,但到1936年底,温石棉已成为唯一使用的石棉类型。在相关期间,只有378名女性受雇,在已死亡的30人中,没有一人的死因通常与接触石棉有关。对男性的死亡率情况分别进行了检查,涉及所有工人、首次接触石棉15年或更长时间后仍在世的所有工人,以及一小群1935 - 1936年受雇且可能接触过青石棉的工人。在这三组中,针对所调查的死因,标准化死亡比(SMR)均未出现明显升高。这些死因包括:所有原因、所有肿瘤、肺癌和胸膜癌以及胃肠道癌。在1964年的首次随访研究中发现的肺癌过量情况在本研究中未被发现。确认了两例胸膜间皮瘤,但在这两例中,男性均在1936年之前就在该工厂工作,因此接触过青石棉。未发现喉癌。