Joseph Chandran Bebisha, Nair S Pradeep
Dermatology, KIMSHEALTH Medical Centre, Doha, QAT.
Dermatology and Venereology, Government T. D. (Thirumala Devaswom) Medical College Alappuzha, Alappuzha, IND.
Cureus. 2025 Feb 5;17(2):e78549. doi: 10.7759/cureus.78549. eCollection 2025 Feb.
Background Acrochordons, otherwise called soft fibromas or skin tags, are small, soft, pedunculated protrusions occurring mainly on the neck and major flexures. They are being investigated as one of the cutaneous markers of diabetes mellitus (DM). The objective of the study was to analyze the clinico-morphological types of acrochordons and to study the association of acrochordons with DM. Materials and methods A descriptive comparative study was conducted in the dermatology outpatient department of a tertiary care hospital in South India over a period of one year. It included 150 cases with acrochordons and a comparative group with age- and sex-matched individuals without acrochordons. All the clinically confirmed cases and comparative groups were subjected to detailed history, clinical examination, and blood and urine tests, and the details were noted in the standard proforma. Statistical analysis was done using Pearson's Chi-squared test. Results Statistical analysis revealed a statistically significant relationship between skin tags and DM (p = 0.0073). Also, there was a significant association between the duration of skin tags and the duration of DM (p= 0.000). The odds ratio was found to be 1.89, which implies that there is a 1.8 times greater risk of an individual with ST developing DM when compared with an individual without a skin tag. Conclusion Skin tags can be considered as an early marker of impaired carbohydrate metabolism and DM.
背景 软纤维瘤，又称皮赘或皮肤软纤维瘤，是主要出现在颈部和主要褶皱处的小而柔软的带蒂突起。它们正作为糖尿病（DM）的皮肤标志物之一进行研究。本研究的目的是分析软纤维瘤的临床形态学类型，并研究软纤维瘤与糖尿病的关联。材料与方法 在印度南部一家三级护理医院的皮肤科门诊进行了为期一年的描述性比较研究。研究包括150例软纤维瘤患者以及一个由年龄和性别匹配的无软纤维瘤个体组成的对照组。所有临床确诊的病例和对照组均接受详细的病史询问、临床检查以及血液和尿液检查，并将详细信息记录在标准表格中。使用Pearson卡方检验进行统计分析。结果 统计分析显示皮赘与糖尿病之间存在统计学上的显著关系（p = 0.0073）。此外，皮赘的持续时间与糖尿病的病程之间也存在显著关联（p = 0.000）。发现优势比为1.89，这意味着与没有皮赘的个体相比，患有皮赘的个体患糖尿病的风险高1.8倍。结论 皮赘可被视为碳水化合物代谢受损和糖尿病的早期标志物。
