Şahin Ömer, Tanriverdi Halime, Seber Turgut, Taşdemir Arzu
Department of Cardiology, University of Health Sciences, Kayseri City Training and Research Hospital, 38080 Kayseri, Turkey.
Department of Radiology, University of Health Sciences, Kayseri City Training and Research Hospital, 38080 Kayseri, Turkey.
Eur Heart J Case Rep. 2025 Mar 11;9(3):ytaf065. doi: 10.1093/ehjcr/ytaf065. eCollection 2025 Mar.
Lymphomas, which originate from the haematopoietic system, are seldom found in the heart due to the absence of a lymphoid system. Primary cardiac lymphoma is quite rare. Cardiac lymphomas can present with dyspnoea, heart failure, pericardial effusion, and arrhythmia. Given the high mortality rates associated with cardiac masses, swift diagnosis is crucial.
A 46-year-old male patient presented to the emergency department of our hospital with complaints of dyspnoea and palpitations. The patient's electrocardiogram revealed a tachycardia characterized by a wide QRS complex and a heart rate of 234 beats per minute, and an intravenous infusion of amiodarone was immediately started. In the cardiac MRI performed, a mass lesion was observed, which was ∼63 ∗ 30 ∗ 79 mm in size, extending from the right atrium to the superior vena cava and right atrial appendage, infiltrating the free wall of the right ventricle, pericardium, and right atrial wall, and showing distinct diffusion restriction in places. The patient's cardiac MRI was documented with a suspicion for cardiac lymphoma. The patient was referred to haematology clinic and started on rituximab-cyclophosphamide, doxorubicin, vincristine, and prednisone chemotherapy.
The diagnosis of primary cardiac lymphoma is uncommon. Even a mass exceeding 7 cm in size may not be visible on transthoracic echocardiography. The use of cardiac MRI to identify intracardiac masses should be incorporated into the diagnostic process to expedite diagnosis and the initiation of life-saving treatment.
淋巴瘤起源于造血系统,由于心脏缺乏淋巴系统,故而很少在心脏中发现。原发性心脏淋巴瘤极为罕见。心脏淋巴瘤可表现为呼吸困难、心力衰竭、心包积液和心律失常。鉴于心脏肿物相关的高死亡率,快速诊断至关重要。
一名46岁男性患者因呼吸困难和心悸到我院急诊科就诊。患者心电图显示为宽QRS波群心动过速,心率为每分钟234次,立即开始静脉输注胺碘酮。在心脏磁共振成像检查中,观察到一个肿物,大小约为63×30×79 mm,从右心房延伸至上腔静脉和右心耳,浸润右心室游离壁、心包和右心房壁,部分区域显示明显的弥散受限。患者的心脏磁共振成像记录显示怀疑为心脏淋巴瘤。患者被转诊至血液科门诊,并开始接受利妥昔单抗 - 环磷酰胺、阿霉素、长春新碱和泼尼松化疗。
原发性心脏淋巴瘤的诊断并不常见。即使肿物大小超过7 cm,经胸超声心动图也可能无法显示。应将心脏磁共振成像用于识别心内肿物纳入诊断流程,以加快诊断并启动挽救生命的治疗。