Suzuki S S, Smith G K
Exp Neurol. 1985 Jul;89(1):71-89. doi: 10.1016/0014-4886(85)90266-3.
Eighty-one of eighty-five isolated neurons recorded from the rat dorsal hippocampus (Ammon's horn and area dentata) were classifiable into four types according to their firing patterns and behavioral correlates. Sixty-two percent of the total neurons were complex spike cells which fired slowly (less than 2/s) most of the time, but were most active during slow-wave sleep, slightly less active during awake immobility, and least active during awake movement and paradoxical sleep. Theta cells (21% of the total) generally fired much faster than complex spike cells and increased their discharge rate whenever rhythmical slow activity was present in the hippocampal EEG (i.e., during awake movement and paradoxical sleep). The behavioral correlates of seven putative granule cells were similar to those of theta cells. However, the behavior-dependent changes in firing frequency were much more pronounced in the former than in the latter. Three (fast) complex spike cells were observed which fired much faster than any other complex spike cell during all states and showed the behavioral correlates similar to those of theta cells. The complex spike cells, theta cells, and fast complex spike cells were found in both Ammon's horn and dentate hilus. A type of multiunit burst was recorded from the pyramidal cell layer. It occurred most frequently during slow-wave sleep, slightly less frequently during awake immobility, and was virtually absent during awake movement and paradoxical sleep. The multiunit burst was considered to represent a summed activity of synchronously bursting complex spike cells. Possible cellular mechanisms of the state-dependent activities in the different neuronal populations of the hippocampus are discussed.
从大鼠背侧海马体（海马角和齿状回）记录的85个分离神经元中，有81个可根据其放电模式和行为相关性分为四种类型。在所有神经元中，62%为复杂棘波细胞，它们大部分时间放电缓慢（低于2次/秒），但在慢波睡眠期间最为活跃，在清醒不动时活跃度稍低，在清醒运动和异相睡眠期间活跃度最低。θ细胞（占总数的21%）通常放电速度比复杂棘波细胞快得多，并且每当海马脑电图出现节律性慢活动时（即清醒运动和异相睡眠期间），其放电频率就会增加。七个假定的颗粒细胞的行为相关性与θ细胞相似。然而，前者放电频率的行为依赖性变化比后者更为明显。观察到三个（快速）复杂棘波细胞，它们在所有状态下的放电速度都比任何其他复杂棘波细胞快得多，并且表现出与θ细胞相似的行为相关性。复杂棘波细胞、θ细胞和快速复杂棘波细胞在海马角和齿状回中均有发现。从锥体细胞层记录到一种多单位爆发。它在慢波睡眠期间出现的频率最高，在清醒不动时出现的频率稍低，在清醒运动和异相睡眠期间几乎不存在。这种多单位爆发被认为代表同步爆发的复杂棘波细胞的总和活动。本文讨论了海马体不同神经元群体中状态依赖性活动的可能细胞机制。
