de Faria Vinícius Borges, Silva Camila Costa, Damaso Patrícia de Paula, Savoldi Igor Ricardo, Sommerfeld Simone, Fonseca Belchiolina Beatriz
University of São Paulo, Brazil; INATA Biológicos, Brazil.
INATA Biológicos, Brazil.
Poult Sci. 2025 May;104(5):104964. doi: 10.1016/j.psj.2025.104964. Epub 2025 Feb 28.
This study conducted a comprehensive survey of Fowl Adenovirus (FAdV), Astrovirus (CAstV), and Avian Reovirus (ARV) in Brazilian poultry, aiming to understand their epidemiological aspects. A total of 1,988 commercial flocks were analyzed across various Brazilian states, resulting in 4,568 analyses. The findings indicated a 25.5 % positivity rate among flocks showing suggestive symptoms, with at least one virus detected in all industrial poultry-producing states. Single-agent infections were more prevalent than co-infections. Among states with over 100 flocks analyzed, the highest FAdV prevalence was found in Santa Catarina and Paraná, while Rio Grande do Sul and Goiás showed the highest CAstV prevalence. For ARV, São Paulo, Rio Grande do Sul, Paraná, and Goiás had the highest rates. FAdV or CAstV were primarily isolated from the intestine (79.69 % and 78.17 %, respectively), whereas ARV was often detected in both the intestine (58.61 %) and tendons (48.01 %). All positive flocks were under 70 days old; chicks younger than 14 days were more likely to test positive for CAstV, while those aged 15 to 70 days showed higher positivity for ARV or co-infections of FAdV and ARV. Notably, strong associations were found between leg problems and ARV (OR = 5.33) or mixed infections (OR = 10.60), as well as between white chicks and CAstV (OR = 5.15) and diarrhea linked to CAstV (OR = 7.27). Regarding gross lesions, significant associations included gizzard erosion with FAdV (OR = 8.20), liver lesions with FAdV (OR = 4.28), and arthritis with ARV (OR = 2.84). In 2023, FAdV strains identified included Aviadenovirus A (A. ventriculi), B (A. quintum), D (A. gallinae), and E (A. hepatitidis). This research underscores the substantial impact of these viruses on Brazilian poultry farming and emphasizes the urgent need for enhanced surveillance and control measures to mitigate their effects on poultry production.
本研究对巴西家禽中的禽腺病毒（FAdV）、星状病毒（CAstV）和禽呼肠孤病毒（ARV）进行了全面调查，旨在了解它们的流行病学特征。在巴西各个州共分析了1988个商业鸡群，进行了4568次检测。结果表明，出现疑似症状的鸡群中阳性率为25.5%，在所有工业化家禽生产州均检测到至少一种病毒。单病毒感染比混合感染更为普遍。在分析鸡群数量超过100个的州中，圣卡塔琳娜州和巴拉那州的FAdV流行率最高，而南里奥格兰德州和戈亚斯州的CAstV流行率最高。对于ARV，圣保罗州、南里奥格兰德州、巴拉那州和戈亚斯州的感染率最高。FAdV或CAstV主要从肠道分离得到（分别为79.69%和78.17%），而ARV常在肠道（58.61%）和肌腱（48.01%）中检测到。所有阳性鸡群均小于70日龄；14日龄以下的雏鸡感染CAstV的可能性更高，而15至70日龄的雏鸡感染ARV或FAdV与ARV混合感染的阳性率更高。值得注意的是，发现腿部问题与ARV（比值比=5.33）或混合感染（比值比=10.60）之间存在强关联，白羽鸡与CAstV（比值比=5.15）以及与CAstV相关的腹泻（比值比=7.27）之间也存在强关联。关于肉眼病变，显著关联包括腺胃糜烂与FAdV（比值比=8.20）、肝脏病变与FAdV（比值比=4.28）以及关节炎与ARV（比值比=2.84）。2023年鉴定出的FAdV毒株包括禽腺病毒A（A. ventriculi）、B（A. quintum）、D（A. gallinae）和E（A. hepatitidis）。本研究强调了这些病毒对巴西家禽养殖的重大影响，并强调迫切需要加强监测和控制措施，以减轻它们对家禽生产的影响。
