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在中国东北可能因接触梅花鹿而出现的一组家庭感染病例。

A family cluster of infections possibly due to contact with a sika deer in Northeast China.

作者信息

Li Kun, Cheng Dawei, Xing Zhifeng, Fan Yu, Xu Qingqing, Chen Xueying, Li Meinan, Zhao Hongyan, Piao Dongri, Jiang Hai

机构信息

National Key Laboratory of Intelligent Tracing and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, Changping, China.

Department of Infectious Diseases, The General Hospital of Beidahuang Group, Harbin, Heilongjiang, China.

出版信息

Future Microbiol. 2025 Apr;20(5):391-394. doi: 10.1080/17460913.2025.2479297. Epub 2025 Mar 19.

DOI:10.1080/17460913.2025.2479297
PMID:40105372
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11980451/
Abstract

Brucellosis is one of the most common zoonotic diseases worldwide. Although deer are reportedly infected by spp., deer-associated brucellosis cases have been rare. In this study, two patients in Heilongjiang Province, Northeast China, were diagnosed with brucellosis. They have contacted a sick sika deer before onset which was bought from another province, but have no contact with other infection sources. Molecular genotyping indicated that both were infected with . This might be the first human cases caused by deer-associated strains despite the frequent reports of in deer. The role of deer in the transmission of should be taken into consideration.

摘要

布鲁氏菌病是全球最常见的人畜共患病之一。尽管据报道鹿可感染布鲁氏菌属,但与鹿相关的布鲁氏菌病病例却很罕见。在本研究中,中国东北黑龙江省的两名患者被诊断为布鲁氏菌病。他们在发病前接触过从另一个省份购买的患病梅花鹿,但未接触过其他传染源。分子基因分型表明两人均感染了布鲁氏菌。尽管鹿中布鲁氏菌感染报告频繁,但这可能是首例由与鹿相关的布鲁氏菌菌株引起的人类病例。应考虑鹿在布鲁氏菌传播中的作用。

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本文引用的文献

1
Global Estimate of Human Brucellosis Incidence.全球人类布鲁氏菌病发病估计数。
Emerg Infect Dis. 2023 Sep;29(9):1789-1797. doi: 10.3201/eid2909.230052.
2
Molecular epidemiological characteristics of in Guizhou Province, China, from 2009 to 2021.2009年至2021年中国贵州省[此处原文缺失关键信息]的分子流行病学特征
Front Microbiol. 2023 Jun 23;14:1188469. doi: 10.3389/fmicb.2023.1188469. eCollection 2023.
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Spatio-Temporal Distribution of Brucellosis in European Terrestrial and Marine Wildlife Species and Its Regional Implications.布鲁氏菌病在欧洲陆地和海洋野生动物物种中的时空分布及其区域影响
Microorganisms. 2022 Oct 5;10(10):1970. doi: 10.3390/microorganisms10101970.
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The Retrospective on Atypical Species Leads to Novel Definitions.对非典型物种的回顾引出了新的定义。
Microorganisms. 2022 Apr 14;10(4):813. doi: 10.3390/microorganisms10040813.
5
First Isolation and Multilocus Sequence Typing of from a Subclinically Infected Pet Dog in China.中国一只亚临床感染宠物狗的首次分离及多位点序列分型
Vet Sci. 2022 Jan 10;9(1):22. doi: 10.3390/vetsci9010022.
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Epidemiological Survey of First Human Brucellosis Outbreak Caused by the Sika Deer () - Guizhou Province, China, 2019.中国贵州省梅花鹿引发的首例人间布鲁氏菌病疫情流行病学调查()-2019年
China CDC Wkly. 2021 Apr 2;3(14):301-303. doi: 10.46234/ccdcw2021.081.
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Risk factors and Molecular genotyping of strains recovered from humans and their owned cattle in Upper Egypt.埃及上埃及地区从人类及其饲养的牛身上分离出的菌株的危险因素和分子基因分型
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