Adler Stephan O, Kitashova Anastasia, Bulović Ana, Nägele Thomas, Klipp Edda
Theoretical Biophysics, Institute of Biology, Humboldt-Universität zu Berlin, Berlin, Germany.
Plant Evolutionary Cell Biology, Faculty of Biology, Ludwig-Maximilians-Universität München, Planegg-Martinsried, München, Germany.
NPJ Syst Biol Appl. 2025 Mar 19;11(1):28. doi: 10.1038/s41540-025-00505-1.
The ability to acclimate to changing environmental conditions is essential for the fitness and survival of plants. Not only are seasonal differences challenging for plants growing in different habitats but, facing climate change, the likelihood of encountering extreme weather events increases. Previous studies of acclimation processes of Arabidopsis thaliana to changes in temperature and light conditions have revealed a multigenic trait comprising and affecting multiple layers of molecular organization. Here, a combination of experimental and computational methods was applied to study the effects of changing light intensities during cold acclimation on the central carbohydrate metabolism of Arabidopsis thaliana leaf tissue. Mathematical modeling, simulation and sensitivity analysis suggested an important role of hexose phosphate balance for stabilization of photosynthetic CO fixation. Experimental validation revealed a profound effect of temperature on the sensitivity of carbohydrate metabolism.
适应不断变化的环境条件的能力对于植物的健康生长和生存至关重要。不仅季节性差异对生长在不同栖息地的植物具有挑战性，而且面对气候变化，遭遇极端天气事件的可能性也在增加。先前对拟南芥适应温度和光照条件变化过程的研究揭示了一种多基因性状，该性状包含并影响分子组织的多个层面。在此，运用实验和计算方法相结合的方式，研究了冷驯化期间光照强度变化对拟南芥叶片组织中心碳水化合物代谢的影响。数学建模、模拟和敏感性分析表明，磷酸己糖平衡对于稳定光合二氧化碳固定具有重要作用。实验验证揭示了温度对碳水化合物代谢敏感性具有深远影响。
