Huang Zhentao, Yang Yuyao, Ma Yahong, Dong Qi, Su Jianyun, Shi Hangyu, Zhang Shanwen, Hu Liangliang
School of Electronic Information and Xi'an Key Laboratory of High Precision Industrial Intelligent Vision Measurement Technology, Xijing University, Xi'an, 710123, China.
College of Computer Science and Technology, Chongqing University of Posts and Telecommunications, Chongqing, 400065, China.
Sci Rep. 2025 Mar 19;15(1):9404. doi: 10.1038/s41598-025-90315-6.
In the field of clinical neurology, automated detection of epileptic seizures based on electroencephalogram (EEG) signals has the potential to significantly accelerate the diagnosis of epilepsy. This rapid and accurate diagnosis enables doctors to provide timely and effective treatment for patients, significantly reducing the frequency of future epileptic seizures and the risk of related complications, which is crucial for safeguarding patients' long-term health and quality of life. Presently, deep learning techniques, particularly Convolutional Neural Networks (CNNs) and Long Short-Term Memory networks (LSTMs), have demonstrated remarkable accuracy improvements across various domains. Consequently, researchers have utilized these methodologies in studies focused on recognizing epileptic signals through EEG analysis. However, current models based on CNN and LSTM still heavily rely on data preprocessing and feature extraction steps. Additionally, CNNs exhibit limitations in perceiving global dependencies, while LSTMs encounter challenges such as gradient vanishing in long sequences. This paper introduced an innovative EEG recognition model, that is the Spatio-temporal feature fusion epilepsy EEG recognition model with dual attention mechanism (STFFDA). STFFDA is comprised of a multi-channel framework that directly interprets epileptic states from raw EEG signals, thereby eliminating the need for extensive data preprocessing and feature extraction. Notably, our method demonstrates impressive accuracy results, achieving 95.18% and 77.65% on single-validation tests conducted on the datasets of CHB-MIT and Bonn University, respectively. Additionally, in the 10-fold cross-validation tests, their accuracy rates were 92.42% and 67.24%, respectively. In summary, it is demonstrated that the seizure detection method STFFD based on EEG signals has significant potential in accelerating diagnosis and improving patient prognosis, especially since it can achieve high accuracy rates without extensive data preprocessing or feature extraction.
在临床神经学领域,基于脑电图(EEG)信号自动检测癫痫发作有潜力显著加快癫痫的诊断。这种快速准确的诊断使医生能够为患者提供及时有效的治疗,显著降低未来癫痫发作的频率以及相关并发症的风险,这对于保障患者的长期健康和生活质量至关重要。目前,深度学习技术,特别是卷积神经网络(CNN)和长短期记忆网络(LSTM),在各个领域都显示出显著的精度提升。因此,研究人员已将这些方法用于专注于通过脑电图分析识别癫痫信号的研究中。然而,当前基于CNN和LSTM的模型仍严重依赖数据预处理和特征提取步骤。此外,CNN在感知全局依赖性方面存在局限性,而LSTM在长序列中会遇到梯度消失等挑战。本文介绍了一种创新的脑电图识别模型,即具有双注意力机制的时空特征融合癫痫脑电图识别模型(STFFDA)。STFFDA由一个多通道框架组成,该框架直接从原始脑电图信号中解读癫痫状态,从而无需进行大量的数据预处理和特征提取。值得注意的是,我们的方法展示了令人印象深刻的准确率结果,在CHB - MIT数据集和波恩大学数据集上进行的单验证测试中,分别达到了95.18%和77.65%。此外,在10折交叉验证测试中,它们的准确率分别为92.42%和67.24%。总之,结果表明基于脑电图信号的癫痫发作检测方法STFFD在加速诊断和改善患者预后方面具有巨大潜力,特别是因为它无需大量数据预处理或特征提取就能实现高准确率。