Friese Carrie
Department of Sociology, London School of Economics and Political Science, London, UK.
Sci Technol Human Values. 2025 Mar;50(2):299-320. doi: 10.1177/01622439241276276. Epub 2024 Aug 28.
The clinician-scientist is often viewed as the crucial nexus in the translational processes that turn scientific research into medical technologies, including but not limited to pharmaceuticals. To create a point of contrast, and to consider the theme of invisible labor, this paper foregrounds an alternative actant who has also been deemed a vital nexus in translational medicine within Science and Technology Studies: the laboratory animal as model organism. Based on observational research conducted in an animal facility that was caring for laboratory mice as well as the immunological laboratory that was conducting research regarding aging and vaccine uptake using those mice, this paper explores how mouse bodies and animal technicians' knowledge of those mouse bodies are rendered invisible through the everyday flows of translation. I draw on Balka and Star's concept of "shadow bodies" to consider variations in how mouse bodies are understood across the translational process and probe the consequences this has for what knowledge is legitimately produced and by whom. By making the invisible work of mice and of technicians visible, I argue that the organizational filters of translational medicine may inadvertently make the work of animal technicians all the harder, in a manner that reproduces social inequalities.
临床科学家通常被视为将科学研究转化为医疗技术(包括但不限于药物)的转化过程中的关键纽带。为了形成对比,并考虑无形劳动的主题,本文突出了另一个行动者,它在科学技术研究领域也被视为转化医学中的重要纽带:作为模式生物的实验动物。基于在一个照料实验小鼠的动物设施以及一个使用这些小鼠进行衰老和疫苗摄取研究的免疫实验室中进行的观察性研究,本文探讨了小鼠身体以及动物技术人员对这些小鼠身体的知识是如何在日常转化流程中变得无形的。我借鉴了巴尔卡和斯塔的“影子身体”概念,来思考在整个转化过程中对小鼠身体理解的差异,并探究这对合法产生的知识以及由谁产生知识所带来的后果。通过使小鼠和技术人员的无形工作变得可见,我认为转化医学的组织过滤器可能会不经意间让动物技术人员的工作变得更加艰难,从而再现社会不平等。