Xu Fan, Zhong Xiaoli, Li Qiao, Luo Xi, Wang Na, Wang Jing, Xie Shaoju, Zhang Jiquan
Oncology Department, Deyang People's Hospital, Sichuan, People's Republic of China.
Nursing Department, Deyang People's Hospital, Sichuan, People's Republic of China.
Cancer Manag Res. 2025 Mar 17;17:603-615. doi: 10.2147/CMAR.S510811. eCollection 2025.
Improving the quality of life (QOL) of lung cancer patients undergoing chemotherapy is an indispensable part of cancer treatment, as it not only pertains to their physical health but also to their psychological and social well-being. Previous research has primarily focused on investigating health-related quality of life, while studies specifically addressing the QOL of lung cancer patients remain underrepresented and under researched.
The study aims to investigate the current status of QOL among lung cancer patients and identify the predictive factors associated with QOL.
From January 2024 to June 2024, lung cancer patients undergoing chemotherapy will be recruited from the outpatient clinics or wards of a tertiary A-level hospital in Deyang City as research subjects. They will be surveyed using the general information questionnaire, the Self-rating Depression Scale (SDS), the Multidimensional Scale of Perceived Social Support (MSPSS), and the Functional Assessment of Cancer Therapy-Lung (FACT-L) scale. Multiple linear regression analysis will be employed to determine the variables associated with QOL.
A total of 390 lung cancer patients undergoing chemotherapy were recruited for this study, with a male predominance accounting for 72.31%. The mean age was (59.11±11.37) years. The overall QOL score was (66.43±23.67). Age, family monthly income per capita, cancer clinical stage, depression, and perceived social support (PSS) were identified as independent factors influencing the QOL of lung cancer patients, accounting for 19.4% of the total variance.
There is still considerable room for improvement in the overall QOL of lung cancer patients undergoing chemotherapy. Based on the analysis of influencing factors, targeted and personalized intervention measures should be implemented to enhance the QOL for these patients.
提高接受化疗的肺癌患者的生活质量（QOL）是癌症治疗中不可或缺的一部分，因为这不仅关乎他们的身体健康，还涉及心理和社会福祉。以往研究主要集中在调查与健康相关的生活质量，而专门针对肺癌患者生活质量的研究仍然较少且研究不足。
本研究旨在调查肺癌患者生活质量的现状，并确定与生活质量相关的预测因素。
2024年1月至2024年6月，将从德阳市一家三级甲等医院的门诊或病房招募接受化疗的肺癌患者作为研究对象。使用一般信息问卷、自评抑郁量表（SDS）、多维感知社会支持量表（MSPSS）和癌症治疗功能评估-肺癌（FACT-L）量表对他们进行调查。将采用多元线性回归分析来确定与生活质量相关的变量。
本研究共招募了390例接受化疗的肺癌患者，男性占主导，占72.31%。平均年龄为（59.11±11.37）岁。总体生活质量得分为（66.43±23.67）。年龄、家庭人均月收入、癌症临床分期、抑郁和感知社会支持（PSS）被确定为影响肺癌患者生活质量的独立因素，占总方差的19.4%。
接受化疗的肺癌患者的总体生活质量仍有很大的提升空间。基于对影响因素的分析，应实施有针对性的个性化干预措施，以提高这些患者的生活质量。
