探索：研究其在蚯蚓和等足类动物模型中对紫外线C辐射的防护潜力的植物化学成分。
Exploring the phytochemical composition of : investigating its protective potential against UV-C radiation in earthworms and isopods models.
作者信息
Eldeen Ahmed Z Ezz, El-Aziz Fatma El-Zahraa A Abd, Sayed Ahmed M, Mousa Sayed A S, Asmaey Mostafa A
机构信息
Department of Chemistry, Faculty of Science, Al-Azhar University, Assiut Branch, Assiut, 71524 Egypt.
Zoology and Entomology Department, Faculty of Science, Assiut University, Assiut, 71516 Egypt.
出版信息
3 Biotech. 2025 Apr;15(4):97. doi: 10.1007/s13205-025-04233-5. Epub 2025 Mar 23.
The aqueous ethanolic extract of (AEESI) demonstrated significant protective effects against UV-C radiation damage, using earthworms and isopods as models for human skin and eyes, respectively. High-performance liquid chromatography (HPLC) analysis identified 15 bioactive polyphenolic compounds in AEESI, with chlorogenic acid (55.51 µg/ml) and gallic acid (46.69 µg/ml) as the dominant phenolic acids, and naringenin (40.42 µg/ml) as the primary flavonoid. The extract effectively mitigated histological and ultrastructural damage caused by UV-C radiation in both models. Additionally, quality control parameters, including moisture content, pH, acidity index, ash content, and elemental composition, were determined for the first time. These findings highlight the potential of extract as a protective agent against UV-C radiation-induced damage, attributed to its rich polyphenolic content.
以蚯蚓和等足类动物分别作为人类皮肤和眼睛的模型，[提取物名称]的乙醇水提取物（AEESI）对紫外线-C辐射损伤显示出显著的保护作用。高效液相色谱（HPLC）分析在AEESI中鉴定出15种具有生物活性的多酚化合物，其中绿原酸（55.51μg/ml）和没食子酸（46.69μg/ml）为主要酚酸，柚皮素（40.42μg/ml）为主要黄酮类化合物。该提取物有效减轻了两种模型中紫外线-C辐射引起的组织学和超微结构损伤。此外，首次测定了包括水分含量、pH值、酸度指数、灰分含量和元素组成在内的质量控制参数。这些发现突出了[提取物名称]提取物作为一种抗紫外线-C辐射诱导损伤保护剂的潜力，这归因于其丰富的多酚含量。
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