Sun Xiao, Zhai Jiancheng
Natural Reserve Planning and Research Institute, East China University of Technology, Nanchang 330013, China.
College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330029, China.
Microorganisms. 2025 Mar 17;13(3):673. doi: 10.3390/microorganisms13030673.
Gut microbiota plays an important role in gut health, and its dysbiosis is closely related to the pathogenesis of various intestinal diseases. The field of gut microbiota and intestinal diseases has not yet been systematically quantified through bibliometric methods. This study conducted bibliometric analysis to delineate the evolution of research on gut microbiota and intestinal diseases. Data were sourced from the Web of Science Core Collection database from 2009 to 2023 and were scientometrically analyzed using CiteSpace. We have found that the number of annual publications has been steadily increasing and showing an upward trend. China and the Chinese Academy of Sciences are the country and institution with the most contributions, respectively. and are the journals with the most publications, while and are the journals with the most citations. The field has shifted from focusing on traditional descriptive analysis of gut microbiota composition to exploring the causal relationship between gut microbiota and intestinal diseases. The research hotspots and trends mainly include the correlation between specific intestinal diseases and gut microbiota diversity, the mechanism of gut microbiota involvement in intestinal diseases, the exploration of important gut microbiota related to intestinal diseases, and the relationship between gut microbiota and human gut health. This study provides a comprehensive knowledge map of gut microbiota and intestinal diseases, highlights key research areas, and outlines potential future directions.
肠道微生物群在肠道健康中发挥着重要作用，其失调与各种肠道疾病的发病机制密切相关。肠道微生物群与肠道疾病领域尚未通过文献计量学方法进行系统量化。本研究进行了文献计量分析，以描绘肠道微生物群与肠道疾病研究的演变。数据来源于2009年至2023年的Web of Science核心合集数据库，并使用CiteSpace进行科学计量分析。我们发现年度出版物数量一直在稳步增加并呈上升趋势。中国和中国科学院分别是贡献最大的国家和机构。 和 是发表论文最多的期刊，而 和 是被引次数最多的期刊。该领域已从专注于肠道微生物群组成的传统描述性分析转向探索肠道微生物群与肠道疾病之间的因果关系。研究热点和趋势主要包括特定肠道疾病与肠道微生物群多样性之间的相关性、肠道微生物群参与肠道疾病的机制、与肠道疾病相关的重要肠道微生物群的探索以及肠道微生物群与人类肠道健康之间的关系。本研究提供了肠道微生物群与肠道疾病的全面知识图谱，突出了关键研究领域，并概述了潜在的未来方向。
