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Keeping it in the family: Malignant Hyperthermia - how we predict, recognise and treat it.家族遗传:恶性高热——我们如何进行预测、识别及治疗。
Braz J Anesthesiol. 2025 May 28;75(4):844645. doi: 10.1016/j.bjane.2025.844645.

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Cognitive aids in the management of clinical emergencies: a systematic review.认知辅助在临床急症管理中的应用:系统评价。
Anaesthesia. 2023 Mar;78(3):343-355. doi: 10.1111/anae.15939. Epub 2022 Dec 14.
2
Pre-operative exercise and pyrexia as modifying factors in malignant hyperthermia (MH).术前运动和发热作为恶性高热(MH)的修饰因素。
Neuromuscul Disord. 2022 Aug;32(8):628-634. doi: 10.1016/j.nmd.2022.06.003. Epub 2022 Jun 11.
3
Malignant Hyperthermia Preparedness Training: Using Cognitive Aids and Emergency Checklists in the Perioperative Setting.恶性高热防范培训:在围手术期使用认知辅助工具和应急检查表
J Perianesth Nurs. 2022 Feb;37(1):24-28. doi: 10.1016/j.jopan.2020.09.020. Epub 2021 Nov 1.
4
The current status of malignant hyperthermia.恶性高热的现状
J Biomed Res. 2019 May 30;34(2):75-85. doi: 10.7555/JBR.33.20180089.
5
Recording Out-of-Hospital Cardiac Arrest Treatment via a Mobile Smartphone Application: A Feasibility Simulation Study.通过移动智能手机应用程序记录院外心脏骤停治疗情况:一项可行性模拟研究。
Prehosp Emerg Care. 2019 Mar-Apr;23(2):284-289. doi: 10.1080/10903127.2018.1490838. Epub 2018 Aug 21.
6
Use of Simulation in Performance Improvement.模拟在绩效改进中的应用。
Anesthesiol Clin. 2018 Mar;36(1):63-74. doi: 10.1016/j.anclin.2017.10.001.
7
The use of a checklist improves anaesthesiologists' technical and non-technical performance for simulated malignant hyperthermia management.使用检查表可提高麻醉师在模拟恶性高热管理方面的技术和非技术性能。
Anaesth Crit Care Pain Med. 2018 Feb;37(1):17-23. doi: 10.1016/j.accpm.2017.07.009. Epub 2017 Sep 20.
8
Simulation-based Assessment of the Management of Critical Events by Board-certified Anesthesiologists.基于模拟的对获得董事会认证的麻醉医生危急事件管理的评估。
Anesthesiology. 2017 Sep;127(3):475-489. doi: 10.1097/ALN.0000000000001739.
9
Interactive pediatric emergency checklists to the palm of your hand - How the Pedi Crisis App traveled around the world.将交互式儿科急诊检查表置于掌心——儿科危机应用程序如何走向世界。
Paediatr Anaesth. 2017 Aug;27(8):835-840. doi: 10.1111/pan.13173. Epub 2017 Jun 7.
10
The Development and Implementation of Cognitive Aids for Critical Events in Pediatric Anesthesia: The Society for Pediatric Anesthesia Critical Events Checklists.儿科麻醉危急事件认知辅助工具的制定与实施:儿科麻醉协会危急事件核对清单。
Anesth Analg. 2017 Mar;124(3):900-907. doi: 10.1213/ANE.0000000000001746.

评估麻醉科住院医师对恶性高热的诊断和控制能力:三种真实模拟场景的比较——一项横断面对照研究。

Evaluation of anesthesiology residents in the diagnosis and control of malignant hyperthermia: comparison of three scenarios of realistic simulation ‒ a cross-sectional controlled study.

作者信息

Neville Mariana F L, Guimarães de Almeida Victor, Andrade Pamela Vieira, Santos Joilson Moura, Munechika Masashi, Ferez David, Dos Santos Silva Mary, Canga Leonardo Ayres, Tripoloni Ana Cristina, Girard Thierry, da Silva Helga Cristina Almeida

机构信息

Universidade Federal de São Paulo, Centro de Hipertermia Maligna do Departamento de Anestesiologia, Dor e Terapia Intensiva, São Paulo, SP, Brazil.

Universidade Federal de São Paulo, Centro de Simulação, São Paulo, SP, Brazil.

出版信息

Braz J Anesthesiol. 2025 Mar 28;75(4):844615. doi: 10.1016/j.bjane.2025.844615.

DOI:10.1016/j.bjane.2025.844615
PMID:40158852
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12008681/
Abstract

INTRODUCTION

Simulation-based training is particularly beneficial for rare and life-threatening diseases such as Malignant Hyperthermia (MH). In addition, cognitive aids, including flowcharts and checklists, can be used as guidance in crisis, reducing cognitive demand and simplifying patient care. We assessed the technical and non-technical performance of anesthesiology residents when diagnosing and treating a hypothetical case of MH in three different scenarios.

METHODS

This was an observational, cross-sectional, and controlled study. Pairs of anesthesiology residents participated in a validated high-fidelity MH realistic simulation in one of three different scenarios: 1) Control (no access to cognitive aids), 2) Poster, or 3) Mobile application. Both poster and mobile application provided a flowchart and information related to MH diagnosis and treatment. Demographic data, perceived stress levels, and technical and non-technical skills were registered and compared among the groups.

RESULTS

Thirty residents (5-pairs for each scenario) participated in the simulations. The mean score in the technical skill survey was significantly higher in the poster and mobile application groups compared with the control group (83 [4.4], 83 [3.8], and 74 [8.2], respectively, ANOVA, p = 0.047). A significantly higher score for non-technical skills was also found for the poster and mobile application groups compared with the control group (55 [2.5], 57 [0.8], 52 [2.1], respectively, ANOVA, p = 0.03).

CONCLUSION

In a realistic high-fidelity MH simulation, the participants had satisfactory performance regarding technical and non-technical skills. However, the groups with access to cognitive aids achieved better scores, with no difference between the groups with access to the MH poster and the MH mobile application.

摘要

引言

基于模拟的培训对于诸如恶性高热(MH)等罕见且危及生命的疾病特别有益。此外,认知辅助工具,包括流程图和检查表,可在危机中用作指导,减少认知需求并简化患者护理。我们评估了麻醉科住院医师在三种不同场景下诊断和治疗假设的MH病例时的技术和非技术表现。

方法

这是一项观察性、横断面和对照研究。成对的麻醉科住院医师在三种不同场景之一中参与了经过验证的高保真MH逼真模拟:1)对照组(无法使用认知辅助工具),2)海报组,或3)移动应用程序组。海报组和移动应用程序组均提供了与MH诊断和治疗相关的流程图和信息。记录并比较了各组的人口统计学数据、感知压力水平以及技术和非技术技能。

结果

30名住院医师(每个场景5对)参与了模拟。海报组和移动应用程序组在技术技能调查中的平均得分显著高于对照组(分别为83 [4.4]、83 [3.8]和74 [8.2],方差分析,p = 0.047)。海报组和移动应用程序组在非技术技能方面的得分也显著高于对照组(分别为55 [2.5]、57 [0.8]、52 [2.1],方差分析,p = 0.03)。

结论

在逼真的高保真MH模拟中,参与者在技术和非技术技能方面表现令人满意。然而,能够使用认知辅助工具的组得分更高,能够使用MH海报的组和能够使用MH移动应用程序的组之间没有差异。