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食品制剂中所含大麻籽的生理效应:最新情况

Physiological effects claimed for hemp seeds contained in food preparations: an update.

作者信息

Zovi Andrea, Vitiello Antonio, Vittori Sauro, Borsetta Germana

机构信息

Directorate General for Hygiene, Food Safety and Nutrition, Ministry of Health, Rome; School of Pharmacy, University of Camerino.

Directorate General for Health Prevention, Ministry of Health, Rome.

出版信息

Ital J Food Saf. 2025 May 27;14(2). doi: 10.4081/ijfs.2025.13653. Epub 2025 Mar 31.

DOI:10.4081/ijfs.2025.13653
PMID:40165760
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12186627/
Abstract

Food supplements are one of the most widely marketed food categories in the world. In relation to several cases of adverse effects reported due to the plant substances contained in these products, the attention of the scientific communities and public decision-makers should be directed to the physiological effects that can be attributed to these substances and that encourage their increasing sales to consumers. This is the case of the plant Cannabis sativa L. In order to evaluate the scientific validity of the physiological effects attributable to Cannabis sativa, a bibliographic search was carried out on the evidence published. This short manuscript has highlighted how, despite the presence on the market of a large number of plant substances present in food preparations, there is not always clear evidence to support the physiological effects attributed to these products. As a result, it is essential to monitor the market to safeguard the food safety of consumers worldwide.

摘要

食品补充剂是全球销售最为广泛的食品类别之一。鉴于有几起因这些产品中所含植物物质而报告的不良反应案例,科学界和公共决策者应关注可归因于这些物质的生理效应,正是这些效应促使它们对消费者的销量不断增加。植物大麻(Cannabis sativa L.)便是如此。为了评估可归因于大麻的生理效应的科学有效性,我们对已发表的证据进行了文献检索。这份简短的手稿强调了,尽管市场上存在大量食品制剂中含有的植物物质,但并不总是有明确的证据来支持归因于这些产品的生理效应。因此,监测市场对于保障全球消费者的食品安全至关重要。

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本文引用的文献

1
Food Supplements Marketed Worldwide: A Comparative Analysis Between the European and the U.S. Regulatory Frameworks.全球销售的食品补充剂:欧洲与美国监管框架的比较分析
J Diet Suppl. 2025;22(1):25-40. doi: 10.1080/19390211.2024.2389397. Epub 2024 Sep 2.
2
Dietary management and access to treatment for patients with glucose deficiency syndrome type 1: an overview review with focus on the European regulatory framework.1型葡萄糖缺乏综合征患者的饮食管理与治疗途径:以欧洲监管框架为重点的综述
Eur J Clin Nutr. 2024 Dec;78(12):1058-1063. doi: 10.1038/s41430-024-01490-0. Epub 2024 Aug 10.
3
Advancing nutrition science to meet evolving global health needs.推进营养科学以满足不断变化的全球健康需求。
Eur J Nutr. 2023 Dec;62(Suppl 1):1-16. doi: 10.1007/s00394-023-03276-9. Epub 2023 Nov 28.
4
A Global Overview of Dietary Supplements: Regulation, Market Trends, Usage during the COVID-19 Pandemic, and Health Effects.膳食补充剂的全球概述:监管、市场趋势、在 COVID-19 大流行期间的使用情况以及健康影响。
Nutrients. 2023 Jul 26;15(15):3320. doi: 10.3390/nu15153320.
5
Triacylglycerols and Other Lipids Profiling of Hemp By-Products.大麻副产物的三酰基甘油和其他脂质分析。
Molecules. 2022 Apr 5;27(7):2339. doi: 10.3390/molecules27072339.
6
Dietary supplements and nutraceuticals market growth during the coronavirus pandemic - Implications for consumers and regulatory oversight.新冠疫情期间膳食补充剂和营养保健品市场的增长——对消费者和监管监督的影响
PharmaNutrition. 2021 Dec;18:100282. doi: 10.1016/j.phanu.2021.100282. Epub 2021 Sep 4.
7
Ingestion of a THC-Rich Cannabis Oil in People with Fibromyalgia: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.《内吸富含四氢大麻酚的大麻油治疗纤维肌痛:一项随机、双盲、安慰剂对照临床试验》。
Pain Med. 2020 Oct 1;21(10):2212-2218. doi: 10.1093/pm/pnaa303.
8
Effects of dietary hemp seed oil to sows on fatty acid profiles, nutritional and immune status of piglets.日粮中添加大麻籽油对母猪的影响及其对仔猪脂肪酸谱、营养和免疫状况的作用。
J Anim Sci Biotechnol. 2020 Mar 18;11:28. doi: 10.1186/s40104-020-0429-3. eCollection 2020.
9
Eight-week hempseed oil intervention improves the fatty acid composition of erythrocyte phospholipids and the omega-3 index, but does not affect the lipid profile in children and adolescents with primary hyperlipidemia.为期 8 周的亚麻籽油干预可改善红细胞磷脂的脂肪酸组成和欧米伽-3 指数,但不能改善原发性高脂血症儿童和青少年的血脂谱。
Food Res Int. 2019 May;119:469-476. doi: 10.1016/j.foodres.2018.12.045. Epub 2018 Dec 26.
10
Activity of liver enzymes in multiple sclerosis patients with Hot-nature diet and co-supplemented hemp seed, evening primrose oils intervention.多发性硬化症患者接受热补饮食和联合补充大麻籽油、月见草油干预后的肝酶活性。
Complement Ther Med. 2014 Dec;22(6):986-93. doi: 10.1016/j.ctim.2014.10.004. Epub 2014 Oct 31.