Understanding the role of trehalose in interactions between and .

Mosquito-borne diseases such as chikungunya, dengue, and Zika represent a major burden on global public health. To fight against these arboviruses, vector control strategies are a priority. One existing strategy is based on the use of an endosymbiotic bacterium, , which reduces the transmission of arboviruses by the mosquito a pathogen blocking effect. in . disrupts several pathways of the host's metabolism. Trehalose is a carbohydrate circulating mainly in insect hemolymph and plays a role in numerous mechanisms as energy source or stress recovery molecule and in chitin synthesis. This study explores the importance of trehalose in the interactions between and , and attempts to understand the pathogen blocking effect.