Jones D B, Scott C S, Wright D H, Stein H, Beverley P C, Payne S V, Crawford D H
Hematol Oncol. 1985 Apr-Jun;3(2):133-45. doi: 10.1002/hon.2900030205.
This report describes the phenotypic analysis of a cell line obtained from a female patient with the nodular sclerosing subtype of Hodgkin's disease (HD). The cell line has a neoplastic karyotype and is stable in culture in the absence of feeder layers or growth factors. Phenotypic analysis of this cell line shows that it cannot easily be characterized as either a lymphocyte, macrophage or granulocyte but resembles in its characteristics certain HD lines already described in the literature. The cell line carries the antigen defined by the Ki-1 monoclonal antibody, shows myeloid markers on a proportion of cells and has cytoplasmic UCH-T1.
本报告描述了从一名患有结节硬化型霍奇金病（HD）的女性患者获得的细胞系的表型分析。该细胞系具有肿瘤核型，在无饲养层或生长因子的情况下在培养中稳定。对该细胞系的表型分析表明，它不易被明确归类为淋巴细胞、巨噬细胞或粒细胞，但其特征与文献中已描述的某些HD细胞系相似。该细胞系携带由Ki-1单克隆抗体定义的抗原，一部分细胞显示髓系标志物，并且具有细胞质UCH-T1。
