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输尿管镜检查和肾切开取石术后的最佳支架置入持续时间:系统评价和荟萃分析。

Optimal stenting duration following ureteroscopy and nephrolithotomy: systematic review and meta-analysis.

作者信息

Porto Breno C, Hobaica Nathalie C, Passerotti Carlo C, Sardenberg Rodrigo A S, Otoch Jose P, da Cruz Jose Arnaldo Shiomi

机构信息

Surgical Technique and Experimental Surgery Department, University of São Paulo School of Medicine, São Paulo, SP, Brazil.

International Teaching and Research Institute - Hapvida NotreDame Intermédica, São Paulo, Brazil.

出版信息

BMC Urol. 2025 Apr 7;25(1):76. doi: 10.1186/s12894-025-01765-z.

DOI:10.1186/s12894-025-01765-z
PMID:40189496
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11974034/
Abstract

INTRODUCTION

The optimal duration for ureteral stent placement following ureteroscopy remains unclear, with no consensus on its impact on patient outcomes. This study aims to evaluate the ideal stent duration by comparing post-procedure-related events (PREs) and complications.

METHODS

A comprehensive search of MEDLINE, Embase, Scopus, Cochrane, Web of Science, and Google Scholar identified studies comparing different durations of ureteral stenting after ureteroscopy. The primary outcome was the occurrence of PREs, while secondary outcomes focused on associated complications.

RESULTS

Four studies were included, encompassing 1762 patients with stents removed with ≤ 5 days and 2231 patients with stents removed with ≥ 6 days. The incidence of PREs did not significantly differ between the two groups (OR: 1.26; 95% CI: 0.22-7.25; p = 0.79; I² = 98%). Patients with stent durations ≥ 6 days had higher rates of flank pain and hematuria. In contrast, fever and dysuria were more prevalent in patients with stents removed within 5 days.

CONCLUSION

Although no significant difference was observed in overall PRE rates, the distinct patterns of complications based on stent duration highlight the complexity of determining optimal stent placement time in clinical practice.

摘要

引言

输尿管镜检查后置入输尿管支架的最佳时长仍不明确,对于其对患者预后的影响尚无共识。本研究旨在通过比较术后相关事件(PREs)和并发症来评估理想的支架置入时长。

方法

全面检索MEDLINE、Embase、Scopus、Cochrane、Web of Science和谷歌学术,以确定比较输尿管镜检查后不同时长输尿管支架置入的研究。主要结局是术后相关事件的发生情况,次要结局则聚焦于相关并发症。

结果

纳入四项研究,包括1762例支架在≤5天取出的患者和2231例支架在≥6天取出的患者。两组术后相关事件的发生率无显著差异(比值比:1.26;95%置信区间:0.22 - 7.25;p = 0.79;I² = 98%)。支架置入时长≥6天的患者腰痛和血尿发生率较高。相比之下,支架在5天内取出的患者发热和排尿困难更为普遍。

结论

虽然总体术后相关事件发生率未观察到显著差异,但基于支架置入时长的不同并发症模式凸显了在临床实践中确定最佳支架置入时间的复杂性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a3c/11974034/7964d3b6a9da/12894_2025_1765_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a3c/11974034/b38174c0e8b4/12894_2025_1765_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a3c/11974034/44f2ba8c694c/12894_2025_1765_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a3c/11974034/b97b8ee3fb85/12894_2025_1765_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a3c/11974034/313278ace65a/12894_2025_1765_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a3c/11974034/5b810b6ee49a/12894_2025_1765_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a3c/11974034/2ad00f0247ab/12894_2025_1765_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a3c/11974034/3454990305d9/12894_2025_1765_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a3c/11974034/aa74f9f42e8b/12894_2025_1765_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a3c/11974034/7964d3b6a9da/12894_2025_1765_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a3c/11974034/b38174c0e8b4/12894_2025_1765_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a3c/11974034/44f2ba8c694c/12894_2025_1765_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a3c/11974034/b97b8ee3fb85/12894_2025_1765_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a3c/11974034/313278ace65a/12894_2025_1765_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a3c/11974034/5b810b6ee49a/12894_2025_1765_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a3c/11974034/2ad00f0247ab/12894_2025_1765_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a3c/11974034/3454990305d9/12894_2025_1765_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a3c/11974034/aa74f9f42e8b/12894_2025_1765_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a3c/11974034/7964d3b6a9da/12894_2025_1765_Fig9_HTML.jpg

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