Tabin Daniel, Patterson Nick, Mah Matthew, Reich David
Department of Human Evolutionary Biology, Harvard University, Cambridge, Massachusetts 02138, USA.
Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.
bioRxiv. 2025 Mar 26:2025.03.24.645126. doi: 10.1101/2025.03.24.645126.
In addition to the issues pointed out in Tabin et al , the MZR data from Zhang et. al 2022 are suggestive of high levels of contamination from a source similar to modern Han Chinese, the majority population in the country where MZR was sequenced. In fact, MZR can be modeled entirely as Han-related ancestry and noise. These results raise further concerns about the veracity of the MZR data and thus the paper's historical conclusions.
除了塔宾等人指出的问题外，张等人2022年的MZR数据表明，其受到来自与现代汉族（MZR测序所在国家的主要人口）相似来源的高度污染。事实上，MZR可以完全被建模为与汉族相关的血统和噪声。这些结果进一步引发了对MZR数据真实性的担忧，进而对该论文的历史结论产生质疑。
