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Hepatic elimination--dispersion model.

作者信息

Roberts M S, Rowland M

出版信息

J Pharm Sci. 1985 May;74(5):585-7. doi: 10.1002/jps.2600740522.

DOI:10.1002/jps.2600740522
PMID:4020641
Abstract
摘要

相似文献

1
Hepatic elimination--dispersion model.
J Pharm Sci. 1985 May;74(5):585-7. doi: 10.1002/jps.2600740522.
2
A dispersion model of hepatic elimination: 3. Application to metabolite formation and elimination kinetics.
J Pharmacokinet Biopharm. 1986 Jun;14(3):289-308. doi: 10.1007/BF01106708.
3
The area under the curve of metabolites for drugs and metabolites cleared by the liver and extrahepatic organs. Its dependence on the administration route of precursor drug.肝脏和肝外器官清除的药物及代谢物的代谢物曲线下面积。其对前体药物给药途径的依赖性。
Drug Metab Dispos. 1985 Jan-Feb;13(1):97-101.
4
Prediction of systemic availability from plasma-level data after oral drug administration.
J Pharm Pharmacol. 1973 Mar;25(3):256-7. doi: 10.1111/j.2042-7158.1973.tb10634.x.
5
Metabolic first-pass effects.代谢首过效应。
J Clin Pharmacol. 1986 Nov-Dec;26(8):580-2. doi: 10.1002/j.1552-4604.1986.tb02952.x.
6
Linear and nonlinear kinetics of drug elimination. I. Kinetics on the basis of a single capacity-limited pathway of elimination with or without simultaneous supply-limited elimination.
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7
A dispersion model of hepatic elimination: 1. Formulation of the model and bolus considerations.肝脏消除的弥散模型：1. 模型的建立及大剂量注射的考量
J Pharmacokinet Biopharm. 1986 Jun;14(3):227-60. doi: 10.1007/BF01106706.
8
Critical evaluation of use of effective protein fractions in developing pharmacokinetic models for drug distribution.有效蛋白质组分在药物分布药代动力学模型开发中的应用的批判性评估。
J Pharm Sci. 1974 Nov;63(11):1698-703. doi: 10.1002/jps.2600631106.
9
Hepatic clearance of drugs. I. Theoretical considerations of a "well-stirred" model and a "parallel tube" model. Influence of hepatic blood flow, plasma and blood cell binding, and the hepatocellular enzymatic activity on hepatic drug clearance.药物的肝清除率。I. “充分搅拌”模型和“平行管”模型的理论考量。肝血流量、血浆和血细胞结合以及肝细胞酶活性对肝药物清除率的影响。
J Pharmacokinet Biopharm. 1977 Dec;5(6):625-53. doi: 10.1007/BF01059688.
10
In vivo evaluation of Michaelis-Menten constants of hepatic drug-eliminating systems.肝药物消除系统米氏常数的体内评估
Drug Metab Dispos. 1978 Mar-Apr;6(2):197-200.

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