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抗生素、咽喉痛与风湿热。

Antibiotics, sore throats and rheumatic fever.

作者信息

Howie J G, Foggo B A

出版信息

J R Coll Gen Pract. 1985 May;35(274):223-4.

PMID:4020743
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1960005/
Abstract

From a retrospective study of hospital records, it is calculated that the present incidence of rheumatic fever in Scottish children is 0.6 per 100 000 per year. This is in keeping with recent research from other developed communities. An attempt is made to assess the relative risk of developing rheumatic fever after antibiotic-treated streptococcal sore throats and non-antibiotic-treated streptococcal sore throats. The risk in both cases is low (probably in the order of 1:30 000) and there is no evidence that prescribing antibiotics for prodromal sore throats confers benefit.

摘要

通过对医院记录的回顾性研究计算得出,苏格兰儿童风湿热的当前发病率为每年每10万人中有0.6例。这与其他发达社区的近期研究结果一致。研究试图评估抗生素治疗的链球菌性咽喉炎和未用抗生素治疗的链球菌性咽喉炎后发生风湿热的相对风险。两种情况下的风险都很低(可能约为1:30000),而且没有证据表明为前驱性咽喉炎开抗生素会带来益处。

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本文引用的文献

1
Changes in relative prevalence of various types of heart disease in New England; contrast between 1925 and 1950.新英格兰地区各类心脏病相对患病率的变化;1925年与1950年的对比。
J Am Med Assoc. 1953 May 23;152(4):303-4. doi: 10.1001/jama.1953.03690040007003.
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Acute rheumatic fever. A vanishing disease in suburbia.急性风湿热。一种在郊区逐渐消失的疾病。
JAMA. 1983 Feb 18;249(7):895-8.
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Antibiotics, sore throats and acute nephritis.抗生素、咽喉痛与急性肾炎。
J R Coll Gen Pract. 1983 Dec;33(257):783-6.
4
Incidence of acute rheumatic fever. A suburban community hospital experience during the 1970s.急性风湿热的发病率。20世纪70年代一家郊区社区医院的经历。
Clin Pediatr (Phila). 1983 Dec;22(12):798-801. doi: 10.1177/000992288302201202.
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Streptococcal pharyngitis in the general population. II. The attack rate of rheumatic fever and acute glomerulonephritis in patients.普通人群中的链球菌性咽炎。II. 患者风湿热和急性肾小球肾炎的发病率
J Infect Dis. 1971 Oct;124(4):348-58. doi: 10.1093/infdis/124.4.348.