Du Xiaojia, Yang Leyi, Liu Nan
Beijing Key Laboratory of Energy Conversion and Storage Materials College of Chemistry Beijing Normal University Beijing 100875 China.
Beijing Graphene Institute (BGI) Beijing 100095 China.
Small Sci. 2023 Apr 24;3(7):2300008. doi: 10.1002/smsc.202300008. eCollection 2023 Jul.
Sensing bioelectrical signals is of great significance to understand human disease. Reliable bioelectronic interface is the guarantee of high-quality bioelectrical signals. The unique electrochemical property and the mixed ionic and electrical conductivity of poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) make it an ideal material for the skin/tissue-electronic interface. However, pristine PEDOT:PSS-based devices cannot meet the requirements for practical use. Toward this end, herein, the development of PEDOT:PSS-based electrodes and their most recent advances in sensing bioelectrical signals are summarized. First, the generation mechanism of bioelectrical signals is introduced in detail. Then, according to the characteristics of bioelectrical signals, the requirements of bioelectrodes are discussed. Next, representative achievements for improving conductivity, stretchability, and stability of PEDOT:PSS are introduced. Bioelectrical signals such as electromyogram (EMG), electrocardiogram (ECG), electrooculogram (EOG), and electroencephalogram (EEG) are successfully recorded by these PEDOT:PSS-based electrodes. Finally, a brief summary is provided, and the opportunities and challenges are also discussed.
感知生物电信号对于理解人类疾病具有重要意义。可靠的生物电子界面是高质量生物电信号的保证。聚（3,4-乙撑二氧噻吩）：聚（苯乙烯磺酸盐）（PEDOT:PSS）独特的电化学性质以及离子与电子混合导电性使其成为皮肤/组织-电子界面的理想材料。然而，基于原始PEDOT:PSS的器件无法满足实际应用的要求。为此，本文总结了基于PEDOT:PSS的电极的发展及其在感知生物电信号方面的最新进展。首先，详细介绍了生物电信号的产生机制。然后，根据生物电信号的特点，讨论了生物电极的要求。接下来，介绍了提高PEDOT:PSS导电性、拉伸性和稳定性的代表性成果。这些基于PEDOT:PSS的电极成功记录了肌电图（EMG）、心电图（ECG）、眼电图（EOG）和脑电图（EEG）等生物电信号。最后，给出简要总结，并讨论了机遇与挑战。
