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2024年10月微创胃肠与胶囊诊断的未来(REFLECT)

The Future of Minimally Invasive GI and Capsule Diagnostics (REFLECT), October 2024.

作者信息

Hansen Lea Østergaard, Agache Alexandra, Koulaouzidis Anastasios

机构信息

Department of Surgery, Odense University Hospital, 5700 Svendborg, Denmark.

Department of Clinical Research, University of Southern Denmark, 5230 Odense, Denmark.

出版信息

Diagnostics (Basel). 2025 Mar 27;15(7):859. doi: 10.3390/diagnostics15070859.

DOI:10.3390/diagnostics15070859
PMID:40218208
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11988344/
Abstract

The fifth annual REFLECT (The futuRE oF MinimalLy InvasivE GI and Capsule diagnosTics) symposium, held in October 2024 in Nyborg, Denmark, focused on advancements in minimally invasive gastrointestinal (GI) diagnostics, particularly capsule endoscopy (CE) technologies. Key discussions included clinical updates, innovations in hardware and software, and the growing role of colon CE (CCE) in colorectal cancer screening. The event provided a platform for clinicians, engineers, industry representatives, and scientists to exchange knowledge and present the latest advancements in the field. Discussions covered clinical studies, future research protocols, and technological innovations, with also a notable focus on commercial solutions and expansion of the implementation of capsule endoscopy. The symposium also highlighted the significance of predictive models for patient selection and developments in panenteric CE. Innovative technologies presented included robotics for drug delivery and magnetic endoscopic guidance systems. AI advancements were discussed for their potential to reduce diagnostic fatigue and standardize image interpretation, but ethical concerns and the need for transparent algorithms remain. The importance of multidisciplinary collaboration was emphasized to bridge innovation and clinical practice. Home-based CCE delivery emerged as a promising model, despite mixed results from environmental impact assessments. Overall, REFLECT 2024 reinforced the clinical utility and challenges of capsule-based diagnostics, advocating for ongoing interdisciplinary research to support safe and effective integration into healthcare systems.

摘要

第五届年度REFLECT(微创胃肠道及胶囊诊断的未来)研讨会于2024年10月在丹麦尼堡举行,重点关注微创胃肠道(GI)诊断的进展,特别是胶囊内镜(CE)技术。主要讨论内容包括临床进展、硬件和软件创新,以及结肠胶囊内镜(CCE)在结直肠癌筛查中日益重要的作用。该活动为临床医生、工程师、行业代表和科学家提供了一个交流知识和展示该领域最新进展的平台。讨论涵盖临床研究、未来研究方案和技术创新,同时显著关注商业解决方案和胶囊内镜实施的扩展。研讨会还强调了预测模型对患者选择的重要性以及全肠道CE的发展。展示的创新技术包括用于药物输送的机器人技术和磁性内镜引导系统。讨论了人工智能的进展,其有潜力减少诊断疲劳并使图像解读标准化,但伦理问题和透明算法的需求仍然存在。强调了多学科合作对于弥合创新与临床实践之间差距的重要性。尽管环境影响评估结果不一,但居家CCE递送成为一种有前景的模式。总体而言,2024年REFLECT强化了基于胶囊的诊断的临床实用性和挑战,倡导持续进行跨学科研究,以支持安全有效地融入医疗保健系统。

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本文引用的文献

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Gut microbiome in colorectal cancer: metagenomics from bench to bedside.结直肠癌中的肠道微生物群:从实验室到临床的宏基因组学
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Evaluation of Colon Capsule Utilisation in Europe-CAPTURE EU Survey Findings.欧洲结肠胶囊使用情况评估——CAPTURE欧盟调查结果
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Tailored Polymersomes for Enhanced Oral Drug Delivery: pH-Sensitive Systems for Intestinal Delivery of Immunosuppressants.定制聚合物囊泡用于增强口服药物传递:用于免疫抑制剂肠道传递的 pH 敏感系统。
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