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磨皮临床试验中的种族报告:一项系统评价

Race Reporting in Dermabrasion Clinical Trials: A Systematic Review.

作者信息

Kamboj Sana, Blalock Travis W

机构信息

Ms. Kamboj is with Emory University School of Medicine in Atlanta, Georgia.

Dr. Blalock is with the Department of Dermatology at Emory University School of Medicine in Atlanta, Georgia.

出版信息

J Clin Aesthet Dermatol. 2025 Apr;18(4):28-32.

PMID:40256334
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12007651/
Abstract

OBJECTIVE

The authors sought to determine the frequency and methods of race reporting in dermabrasion clinical trials.

METHODS

A PubMed search for terms: "dermabrasion," "derm-abrasion," and "derm abrasion" was conducted, yielding 1,786 papers. The "Clinical Trial" and "Randomized Control Trial" filters were applied. Non-English manuscripts were excluded. Remaining manuscripts were manually screened. Forty-one papers met final inclusion criteria.

RESULTS

Forty-six percent (n=19) of studies included mention of race, skin color, or Fitzpatrick skin type (FST). Four studies reported FST of 78 dermabrasion participants. Of these, 19 percent had FST I, 27 percent had FST II, 32 percent had FST III, 17 percent had FST IV, and 1 percent had FST V. Three patients (4%) were lost to follow-up and did not have FSTs reported. Twenty-two percent (n=9) of the studies including 513 patients reported race or skin color. The races of 107 (21%) could be definitively extracted. Of these 107 patients, 94 percent were White, five percent were Black, and one percent were Asian.

LIMITATIONS

Our search was limited to PubMed-indexed articles which were categorized as 1) clinical trials or 2) randomized control trials. Articles that were incorrectly indexed in accordance with the search tool may have been inadvertently excluded.

CONCLUSION

Our analysis suggests that the collection and reporting of racial demographic information has been rare in dermabrasion clinical trials. The absence of this demographic information limits the generalizability of the results. Given the health disparities that arise due to racism, investigators should collect and report participant races to improve risk stratification and transparency.

摘要

目的

作者试图确定皮肤磨削术临床试验中种族报告的频率和方法。

方法

在PubMed上搜索“皮肤磨削术”“皮肤磨皮术”和“皮肤磨蚀”等术语,共得到1786篇论文。应用“临床试验”和“随机对照试验”过滤器。排除非英文手稿。对剩余手稿进行人工筛选。41篇论文符合最终纳入标准。

结果

46%(n = 19)的研究提及了种族、肤色或菲茨帕特里克皮肤类型(FST)。四项研究报告了78名皮肤磨削术参与者的FST。其中,19%为FST I型,27%为FST II型,32%为FST III型,17%为FST IV型,1%为FST V型。三名患者(4%)失访,未报告FST。22%(n = 9)的研究纳入了513名患者,报告了种族或肤色。其中107名患者(21%)的种族可以明确提取。在这107名患者中,94%为白人,5%为黑人,1%为亚洲人。

局限性

我们的搜索仅限于PubMed索引的文章,这些文章被归类为1)临床试验或2)随机对照试验。根据搜索工具索引错误的文章可能被无意中排除。

结论

我们的分析表明,在皮肤磨削术临床试验中,种族人口统计学信息的收集和报告很少见。这种人口统计学信息的缺失限制了结果的普遍性。鉴于种族主义导致的健康差异,研究人员应收集和报告参与者的种族,以改善风险分层和透明度。

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本文引用的文献

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Race and Ethnic Categories: A Brief Review of Global Terms and Nomenclature.种族和族裔类别:全球术语和命名法简述
Cureus. 2023 Jul 1;15(7):e41253. doi: 10.7759/cureus.41253. eCollection 2023 Jul.
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Racial and ethnic underrepresentation in dermatology clinical trials.皮肤科临床试验中的种族和民族代表性不足。
J Am Acad Dermatol. 2023 Aug;89(2):293-300. doi: 10.1016/j.jaad.2023.04.011. Epub 2023 Apr 14.
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Dermabrasion Versus Microneedling in Transplantation of Autologous Noncultured Melanocyte-Keratinocyte Cell Suspension in Patients With Vitiligo.磨皮术与微针在白癜风患者自体非培养黑素细胞-角质形成细胞悬液移植中的比较。
Dermatol Surg. 2023 May 1;49(5):494-502. doi: 10.1097/DSS.0000000000003738. Epub 2023 Mar 8.
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Racial disparities in dermatology.皮肤科的种族差异。
Arch Dermatol Res. 2023 Jul;315(5):1215-1223. doi: 10.1007/s00403-022-02507-z. Epub 2022 Dec 12.
5
Post-Inflammatory Hyperpigmentation in Dark Skin: Molecular Mechanism and Skincare Implications.深色皮肤的炎症后色素沉着:分子机制及皮肤护理意义
Clin Cosmet Investig Dermatol. 2022 Nov 25;15:2555-2565. doi: 10.2147/CCID.S385162. eCollection 2022.
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Updated Guidance on the Reporting of Race and Ethnicity in Medical and Science Journals.医学与科学期刊中种族与民族报告的更新指南。
JAMA. 2021 Aug 17;326(7):621-627. doi: 10.1001/jama.2021.13304.
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Pediatr Dermatol. 2021 Nov;38 Suppl 2:167-169. doi: 10.1111/pde.14739. Epub 2021 Aug 6.
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