Güneş Kaya Didem, Bayramoğlu Elvan, Turan Hande, Karaca Enes, Eyüpoğlu Göktuğ Zorbay, Pirdal Betül Zehra, Evliyaoğlu Saadet Olcay
Department of Pediatric, Nutrition and Dietetics PhD, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Department of Pediatric Endocrinology, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, MD, Turkey.
BMC Endocr Disord. 2025 Apr 21;25(1):109. doi: 10.1186/s12902-025-01917-0.
This study aimed to assess the impact of recurrent individualized education on the management of hypoglycemia, hypoglycemia awareness, and metabolic control of diabetes in children and adolescents living with type 1 diabetes (T1D).
A prospective quantitative study involving participants aged 8 to 18 years with T1D was conducted. Three established hypoglycemia screening tools were employed: the Hypoglycemia Fear Survey (HFS), the Gold Hypoglycemia Awareness Questionnaire, and the Edinburgh Hypoglycemia Symptoms Scale. The participants used blinded continuous glucose monitoring (b-CGM) devices to document glucose values, meals, insulin doses, exercise periods, symptomatic hypoglycemia episodes, and glucose levels during hypoglycemia, experienced symptoms, and treatment approaches for hypoglycemia. Following this initial phase, the participants received education from healthcare professionals. The same procedures were repeated six weeks after the educational intervention.
Prior to education, approximately half (n = 21) of the 47 participants were present with impaired hypoglycemia awareness (IHA), and half of the IHA group applied the appropriate hypoglycemia self-treatment. After education, almost all participants demonstrated an improved ability to manage hypoglycemia effectively. Following education, improvements in the frequency of fingerstick glucose measurement per day, time spent within the target glucose range (70-180 mg/dL), glycemic variability (GV), hypoglycemia perception, appropriate hypoglycemia self-treatment, and hypoglycemia fear were observed, both in participants with hypoglycemia awareness and those with IHA.
The results indicate that children and adolescents living with T1D benefit from recurrent self-management education. The benefits were observed in both participants with hypoglycemia awareness and those with IHA. Education positively impacts diabetes management and enhances hypoglycemia awareness.
本研究旨在评估反复进行的个体化教育对1型糖尿病(T1D)儿童和青少年低血糖管理、低血糖意识及糖尿病代谢控制的影响。
对8至18岁的T1D参与者进行了一项前瞻性定量研究。采用了三种既定的低血糖筛查工具:低血糖恐惧调查(HFS)、金标准低血糖意识问卷和爱丁堡低血糖症状量表。参与者使用盲法连续血糖监测(b-CGM)设备记录血糖值、饮食、胰岛素剂量、运动时段、有症状的低血糖发作、低血糖期间的血糖水平、经历的症状以及低血糖的治疗方法。在这个初始阶段之后,参与者接受了医疗保健专业人员的教育。教育干预六周后重复相同程序。
教育前,47名参与者中约一半(n = 21)存在低血糖意识受损(IHA),且IHA组中有一半采用了适当的低血糖自我治疗。教育后,几乎所有参与者有效管理低血糖的能力都有所提高。教育后,在有低血糖意识的参与者和有IHA的参与者中,均观察到每日指尖血糖测量频率、血糖目标范围内(70 - 180 mg/dL)的时间、血糖变异性(GV)、低血糖感知、适当的低血糖自我治疗以及低血糖恐惧方面的改善。
结果表明,T1D儿童和青少年受益于反复的自我管理教育。在有低血糖意识的参与者和有IHA的参与者中均观察到了益处。教育对糖尿病管理有积极影响并增强了低血糖意识。