da Silva Emanoelly M S, Ribeiro Paula R, Slaviero Mônica, Gris Anderson H, de Almeida Bruno A, Pereira Vanessa C, Menegatt Jean C O, Bandinelli Marcele B, Panziera Welden, Pavarini Saulo P, Driemeier David, Sonne Luciana
Setor de Patologia Veterinária, Universidade Federal do Rio Grande do Sul, Av. Bento Gonçalves, 9090, Porto Alegre, RS, 91540-000, Brazil.
Setor de Patologia Veterinária, Universidade Federal do Rio Grande do Sul, Av. Bento Gonçalves, 9090, Porto Alegre, RS, 91540-000, Brazil.
J Comp Pathol. 2025 May;219:15-20. doi: 10.1016/j.jcpa.2025.04.001. Epub 2025 Apr 23.
The nasal cavity and paranasal sinuses comprise various tissues that can give rise to different neoplasms, including nasal sarcomas. The aim of this study was to describe the clinicopathological characteristics of canine sinonasal sarcomas. A retrospective study was conducted on 39 dogs, aged between 2 and 18 years old, with a diagnosis of sinonasal sarcoma. The dogs were grouped according to tumour type: 12 nasal chondrosarcomas, 12 osteosarcomas and 15 spindle cell tumours (fibrosarcoma, undifferentiated sarcoma, haemangiosarcoma, myxosarcoma and leiomyosarcoma). Most dogs were mixed breed and there was a predominance of large breeds in the cases of nasal osteosarcoma. Facial deformity, epistaxis and dyspnoea were the most common clinical signs. The tumours affected mainly the nasal region. Metastases were uncommon and found in three cases of nasal spindle cell tumour and one case of chondroblastic osteosarcoma. Furthermore, nasal spindle cell tumours had an increased mitotic index, compared with chondrosarcoma and osteosarcoma, suggesting malignancy.
鼻腔和鼻窦由多种组织构成，这些组织可引发不同的肿瘤，包括鼻肉瘤。本研究的目的是描述犬鼻窦肉瘤的临床病理特征。对39只年龄在2至18岁之间、诊断为鼻窦肉瘤的犬进行了回顾性研究。这些犬根据肿瘤类型分组：12例鼻软骨肉瘤、12例骨肉瘤和15例梭形细胞瘤（纤维肉瘤、未分化肉瘤、血管肉瘤、黏液肉瘤和平滑肌肉瘤）。大多数犬为混血品种，在鼻骨肉瘤病例中大型犬占多数。面部畸形、鼻出血和呼吸困难是最常见的临床症状。肿瘤主要累及鼻腔区域。转移并不常见，在3例鼻梭形细胞瘤和1例软骨母细胞性骨肉瘤病例中发现有转移。此外，与软骨肉瘤和骨肉瘤相比，鼻梭形细胞瘤的有丝分裂指数增加，提示恶性程度较高。
