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个性化地中海饮食可改善纤维肌痛患者的疼痛及生活质量。

A Personalized Mediterranean Diet Improves Pain and Quality of Life in Patients with Fibromyalgia.

作者信息

Casini Ilenia, Ladisa Valeria, Clemente Livio, Delussi Marianna, Rostanzo Elvira, Peparini Sofia, Aloisi Anna Maria, de Tommaso Marina

机构信息

Department of Medicine, Surgery and Neuroscience, University of Siena, Siena, Italy.

Neurophysiopathology Unit, DiBrain Department, Policlinico General Hospital, Bari Aldo Moro University, Piazza Giulio Cesare 11, 70124, Bari, Italy.

出版信息

Pain Ther. 2024 Jun;13(3):609-620. doi: 10.1007/s40122-024-00598-2. Epub 2024 Apr 29.

Abstract

INTRODUCTION

Fibromyalgia is a form of chronic pain that affects a large number of women. It can start at any age and last a lifetime, with no cure. The Mediterranean diet is said to have an anti-inflammatory effect. Therefore, this study was conducted to investigate possible beneficial effects of a personalized Mediterranean diet in patients with fibromyalgia.

METHODS

Outpatients with fibromyalgia were recruited and invited to participate in the study, including clinical, nutritional, and dietary assessments. Patients received a personalized Mediterranean diet (DIET group) or a general balanced diet (NODIET group) to be followed for 8 weeks. All tests were carried out at baseline and repeated after 4 and 8 weeks.

RESULTS

In total, 100 subjects were included, 84 of whom completed the study. Most of the patients showed incorrect habits in terms of food choices, timing of meals and composition of nutrients. The DIET group showed an improvement in most of the fibromyalgia parameters, including the disability scores, fatigue, and anxiety.

CONCLUSIONS

The habit of eating inflammatory foods and/or eating meals with the wrong nutritional content would increase the negative status of patients with fibromyalgia. With this study, we confirm that proper attention to feeding habits would improve the quality of life of such patients.

摘要

引言

纤维肌痛是一种影响众多女性的慢性疼痛形式。它可在任何年龄发病并持续终生,无法治愈。据说地中海饮食具有抗炎作用。因此,本研究旨在调查个性化地中海饮食对纤维肌痛患者可能产生的有益影响。

方法

招募纤维肌痛门诊患者并邀请其参与研究,包括临床、营养和饮食评估。患者接受个性化地中海饮食(饮食组)或一般均衡饮食(非饮食组),为期8周。所有测试均在基线时进行,并在4周和8周后重复进行。

结果

总共纳入100名受试者,其中84人完成了研究。大多数患者在食物选择、用餐时间和营养成分方面存在不良习惯。饮食组在大多数纤维肌痛参数方面有所改善,包括残疾评分、疲劳和焦虑。

结论

食用炎性食物和/或摄入营养成分错误的膳食的习惯会加重纤维肌痛患者的负面状况。通过本研究,我们证实适当关注饮食习惯将改善此类患者的生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c733/11111631/5175d1873388/40122_2024_598_Fig1_HTML.jpg

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