Poulter N R, Khaw K T, Mugambi M, Peart W S, Sever P S
Clin Exp Pharmacol Physiol. 1985 May-Jun;12(3):211-6. doi: 10.1111/j.1440-1681.1985.tb02633.x.
A longitudinal study of the effects of migration on blood pressure and related factors is being carried out in members of a black Kenyan population who migrate from a traditional rural community to an urban environment. Data on the first 139 migrants (78 male, 61 female) and 204 control non-migrants (126 male, 78 female) who have been followed up for a period of 6 months are presented. Blood pressure changes rapidly on migration (within the first 2 months); thereafter trends between migrants and controls differ. Significant differences in systolic pressure between migrants and controls are found at all examinations during the 6 month follow-up in both sexes. Diastolic pressure falls in controls but rises in migrants, the greatest difference being seen at the 6 month examination. Migration is associated with a marked increase in dietary sodium and a fall in potassium demonstrated by measurements of urinary electrolyte excretion in 3 X 12 h or 3 X 24 h urine collections. Analysis of covariance shows that the blood pressure differences between migrants and controls are partly explained by urinary sodium/potassium ratios and in some instances by body weight.
一项关于移民对血压及相关因素影响的纵向研究正在肯尼亚黑人中展开，这些人从传统农村社区迁移至城市环境。本文呈现了对首批139名移民（78名男性，61名女性）和204名非移民对照者（126名男性，78名女性）进行为期6个月随访的数据。移民后血压迅速变化（在头2个月内）；此后，移民与对照者之间的趋势有所不同。在6个月随访期间的所有检查中，男女移民与对照者的收缩压均存在显著差异。对照组舒张压下降，而移民组舒张压上升，在6个月检查时差异最为明显。通过对3次12小时或3次24小时尿液收集进行尿电解质排泄测量表明，移民与饮食中钠的显著增加以及钾的减少有关。协方差分析显示，移民与对照者之间的血压差异部分可由尿钠/钾比值解释，在某些情况下可由体重解释。
