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基于机器学习的腹部手术后死亡风险预测

Machine learning-based prediction of postoperative mortality risk after abdominal surgery.

作者信息

Yuan Ji-Hong, Jin Yong-Mei, Xiang Jing-Ye, Li Shuang-Shuang, Zhong Ying-Xi, Zhang Shu-Liu, Zhao Bin

机构信息

Department of General Surgery, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai 201317, China.

Department of Health Management, Zhenru Community Health Service Center of Putuo District, Shanghai 200333, China.

出版信息

World J Gastrointest Surg. 2025 Apr 27;17(4):103696. doi: 10.4240/wjgs.v17.i4.103696.

DOI:10.4240/wjgs.v17.i4.103696
PMID:40291872
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12019056/
Abstract

BACKGROUND

Preoperative risk assessments are vital for identifying patients at high risk of postoperative mortality. However, traditional scoring systems can be time consuming. We hypothesized that the use of machine learning models would enable rapid and accurate risk assessments to be performed.

AIM

To assess the potential of machine learning algorithms to develop predictive models of mortality risk after abdominal surgery.

METHODS

This retrospective study included 230 individuals who underwent abdominal surgery at the Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine between January 2023 and December 2023. Demographic and surgery-related data were collected and used to develop nomogram, decision-tree, random-forest, gradient-boosting, support vector machine, and naïve Bayesian models to predict 30-day mortality risk after abdominal surgery. Models were assessed using receiver operating characteristic curves and compared using the DeLong test.

RESULTS

Of the 230 included patients, 52 died and 178 survived. Models were developed using the training cohort ( = 161) and assessed using the validation cohort ( = 68). The areas under the receiver operating characteristic curves for the nomogram, decision-tree, random-forest, gradient-boosting tree, support vector machine, and naïve Bayesian models were 0.908 [95% confidence interval (CI): 0.824-0.992], 0.874 (95%CI: 0.785-0.963), 0.928 (95%CI: 0.869-0.987), 0.907 (95%CI: 0.837-0.976), 0.983 (95%CI: 0.959-1.000), and 0.807 (95%CI: 0.702-0.911), respectively.

CONCLUSION

Nomogram, random-forest, gradient-boosting tree, and support vector machine models all demonstrate strong performances for the prediction of postoperative mortality and can be selected based on the clinical circumstances.

摘要

背景

术前风险评估对于识别术后死亡高风险患者至关重要。然而,传统评分系统可能耗时。我们假设使用机器学习模型能够进行快速且准确的风险评估。

目的

评估机器学习算法用于开发腹部手术后死亡风险预测模型的潜力。

方法

这项回顾性研究纳入了2023年1月至2023年12月期间在上海中医药大学附属第七人民医院接受腹部手术的230例患者。收集人口统计学和手术相关数据,并用于开发列线图、决策树、随机森林、梯度提升、支持向量机和朴素贝叶斯模型,以预测腹部手术后30天的死亡风险。使用受试者工作特征曲线评估模型,并使用德龙检验进行比较。

结果

在纳入的230例患者中,52例死亡,178例存活。使用训练队列(=161)开发模型,并使用验证队列(=68)进行评估。列线图、决策树、随机森林、梯度提升树、支持向量机和朴素贝叶斯模型的受试者工作特征曲线下面积分别为0.908[95%置信区间(CI):0.824 - 0.992]、0.874(95%CI:0.785 - 0.963)、0.928(95%CI:0.869 - 0.987)、0.907(95%CI:0.837 - 0.976)、0.983(95%CI:0.959 - 1.000)和0.807(95%CI:0.702 - 0.911)。

结论

列线图、随机森林、梯度提升树和支持向量机模型在预测术后死亡率方面均表现出强大性能,可根据临床情况进行选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b1f/12019056/0cabbafd2de1/103696-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b1f/12019056/1a7ee472445e/103696-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b1f/12019056/3cbeb40b3b7c/103696-g002.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b1f/12019056/ace67e3ccf7e/103696-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b1f/12019056/5fb91030b4fc/103696-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b1f/12019056/3f7115f81ded/103696-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b1f/12019056/0cabbafd2de1/103696-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b1f/12019056/1a7ee472445e/103696-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b1f/12019056/3cbeb40b3b7c/103696-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b1f/12019056/42b2ea853395/103696-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b1f/12019056/ace67e3ccf7e/103696-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b1f/12019056/5fb91030b4fc/103696-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b1f/12019056/3f7115f81ded/103696-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b1f/12019056/0cabbafd2de1/103696-g007.jpg

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