[使用多元逐步回归评估镇痛药与镇静剂组合的止痛特性]
[Evaluation of the pain-alleviating properties of a combination of analgesic and tranquilizer using multiple stepwise regression].
作者信息
Dmitriev A V, Bershadskiĭ B G
出版信息
Farmakol Toksikol. 1985 May-Jun;48(3):33-6.
PMID:4029377
Abstract
A method for preclinical evaluation of the optimal ratio (for analgesia) of an analgesic to a tranquilizer has been devised. It is based on the drug threshold dose decrease on the drug combined use. The multiple stepwise regression analysis of the data discovered the correlations between diazepam and promedol, optimal for pain perception decrease and nociceptive emotional responsiveness inhibition.
摘要
已设计出一种用于临床前评估镇痛药与镇静剂最佳比例（用于镇痛）的方法。它基于联合使用药物时药物阈剂量的降低。对数据进行的多元逐步回归分析发现了地西泮与异丙嗪之间的相关性，这对于降低疼痛感知和抑制伤害性情绪反应最为理想。
相似文献
1
[Evaluation of the pain-alleviating properties of a combination of analgesic and tranquilizer using multiple stepwise regression].[使用多元逐步回归评估镇痛药与镇静剂组合的止痛特性]
Farmakol Toksikol. 1985 May-Jun;48(3):33-6.
2
[Pain-alleviating action of gidifen and its combinations with analgesics].[吉地芬及其与镇痛药联合使用的镇痛作用]
Farmakol Toksikol. 1985 May-Jun;48(3):29-33.
3
[Analysis of the role of various factors of the initial status of the body in the analgesic action of promedol].[分析机体初始状态的各种因素在异丙嗪镇痛作用中的作用]
Farmakol Toksikol. 1984 Jul-Aug;47(4):34-6.
4
[A comparison of the effect of tranquilizers in experiments and clinical practice].[安定剂在实验与临床实践中的效果比较]
Stomatologiia (Mosk). 1991 Mar-Apr(2):22-4.
5
[The analgetic activity of antidepressants and their influence on the pain-relieving effect of acupuncture].[抗抑郁药的镇痛活性及其对针刺镇痛效果的影响]
Farmakol Toksikol. 1991 May-Jun;54(3):12-4.
6
[The spectrum of analgesic activity of baclofen and tolibut].[巴氯芬和托利布特的镇痛活性谱]
Farmakol Toksikol. 1987 Jan-Feb;50(1):24-7.
7
[The characteristics of the analgesic action of nitrosorbide and no-shpa].[亚硝酸异山梨酯与硝苯地平的镇痛作用特点]
Eksp Klin Farmakol. 1998 Jul-Aug;61(4):17-9.
8
[Mechanisms of the antishock action of mebikar].
Farmakol Toksikol. 1984 Mar-Apr;47(2):28-32.
9
[Evaluation of the analgesic action of clofelin in cardiogenic pain (clinico-experimental research)].[氯非林对心源性疼痛的镇痛作用评估（临床实验研究）]
Farmakol Toksikol. 1987 Mar-Apr;50(2):36-9.
10
[The specific analgesic action of morphine on rats in an experimental pain syndrome].[吗啡对实验性疼痛综合征大鼠的特异性镇痛作用]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1989 Mar-Apr;39(2):356-61.
Zotero 插件