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壳聚糖和氯己定对脱矿牙本质增强黏附力的作用。

Effect of chitosan and chlorhexidine on demineraslised dentin to enhance adhesion.

作者信息

Yadahalli Rashmi P, Bahadur Saikiran, Gupta Nisha, Bhardwaj Smita Singh, Priyadarsani Sushree Arpita, Ahmed Almuntashiri Ahmed Ali, Gupta Awadhesh Kumar

机构信息

Department of Conservative Dentistry and Endodontics, PMNM Dental College & Hospital, Bagalkot, Karnataka, India.

Department of Prosthodontics, Springfield Dental, Springfield, Massachusetts, USA.

出版信息

Bioinformation. 2025 Feb 28;21(2):185-188. doi: 10.6026/973206300210185. eCollection 2025.

DOI:10.6026/973206300210185
PMID:40322705
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12044170/
Abstract

The bond strength (BS) and failure status of demineralized dentin following the application of chitosan solution and chlorhexidine (CHX) is of interest to dentists. A total of 30 non-pathological extracted premolar teeth were subjected to caries induction through the pH cycle procedure. The teeth were divided equally into 3 groups as such as group I: control (distilled water), Group II-2.5% chitosan solution and Group III - chlorhexidine (CHX). Later teeth were subjected to a microtensile bond strength test (µTBS). The failure mode was assessed using stereo microscope. The bond strength of the chitosan-treated specimens was significantly higher than that of the chlorhexidine treated specimens and the control specimen which had the lowest bond strength.

摘要

壳聚糖溶液和洗必泰(CHX)应用后脱矿牙本质的粘结强度(BS)和失败状态是牙医感兴趣的。总共30颗非病理性拔除的前磨牙通过pH循环程序进行龋病诱导。牙齿被平均分为3组,即:第一组:对照组(蒸馏水),第二组 - 2.5%壳聚糖溶液,第三组 - 洗必泰(CHX)。随后对牙齿进行微拉伸粘结强度测试(µTBS)。使用立体显微镜评估失败模式。壳聚糖处理标本的粘结强度显著高于洗必泰处理标本和粘结强度最低的对照标本。

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本文引用的文献

1
Effect of chitosan and CMCS on dentin after Er:YAG laser irradiation: shear bond strength and surface morphology analysis.壳聚糖和 CMCS 对 Er:YAG 激光照射后牙本质的影响:剪切粘结强度和表面形貌分析。
BMC Oral Health. 2024 Mar 29;24(1):402. doi: 10.1186/s12903-024-04097-w.
2
Evaluation of Chitosan-Oleuropein Nanoparticles on the Durability of Dentin Bonding.壳聚糖-橄榄苦苷纳米粒子对牙本质粘结耐久性的评价。
Drug Des Devel Ther. 2023 Jan 22;17:167-180. doi: 10.2147/DDDT.S390039. eCollection 2023.
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Evaluation of push-out bond strength of different concentrations of chitosan nanoparticles incorporated composite resin and eighth-generation bonding agent for class II restoration: An study.不同浓度壳聚糖纳米颗粒复合树脂与第八代II类修复粘结剂的推出粘结强度评估:一项研究。
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Chitosan-induced biomodification on demineralized dentin to improve the adhesive interface.壳聚糖诱导的脱矿牙本质生物改性以改善粘结界面。
Restor Dent Endod. 2022 Jun 15;47(3):e28. doi: 10.5395/rde.2022.47.e28. eCollection 2022 Aug.
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Chitosan improves the durability of resin-dentin interface with etch-and-rinse or self-etch adhesive systems.壳聚糖提高了酸蚀-冲洗或自酸蚀黏接系统的树脂-牙本质黏接界面的耐久性。
J Appl Oral Sci. 2021 Dec 13;29:e20210356. doi: 10.1590/1678-7757-2021-0356. eCollection 2021.
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Effect of Chitosan as a Cross-Linker on Matrix Metalloproteinase Activity and Bond Stability with Different Adhesive Systems.壳聚糖作为交联剂对不同粘接系统基质金属蛋白酶活性和粘接稳定性的影响。
Mar Drugs. 2020 May 18;18(5):263. doi: 10.3390/md18050263.
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Oral Soft Tissue Regeneration Using Nano Controlled System Inducing Sequential Release of Trichloroacetic Acid and Epidermal Growth Factor.采用纳米控制体系诱导三氯乙酸和表皮生长因子顺序释放实现口腔软组织再生。
Tissue Eng Regen Med. 2020 Feb;17(1):91-103. doi: 10.1007/s13770-019-00232-9. Epub 2020 Jan 22.
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Eur J Oral Sci. 2019 Feb;127(1):81-88. doi: 10.1111/eos.12584. Epub 2018 Nov 9.
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Chitosan-Based Extrafibrillar Demineralization for Dentin Bonding.基于壳聚糖的纤维外脱矿在牙本质粘结中的应用。
J Dent Res. 2019 Feb;98(2):186-193. doi: 10.1177/0022034518805419. Epub 2018 Oct 16.
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Effect of different concentrations of chlorhexidine on bond strength of primary dentin.不同浓度洗必泰对乳牙本质粘结强度的影响
Pediatr Dent. 2012 Mar-Apr;34(2):e11-5.