Okamura K, Nakakuki M, Nagai H, Koga S, Akama J
Jpn J Antibiot. 1985 Apr;38(4):911-4.
Clinical study to evaluate the usefulness of cefpimizole (AC-1370) was made in the 6 patients with female genital organ infections. Two grams or 4 g of AC-1370 was administered a day by intravenous drip infusion ranging from 5 to 18 days. Responses were excellent in 2 cases, good in 3 cases and poor in 1 case, parametritis after hysterectomy. The efficacy rate was 83%. Neither general side effect nor abnormal laboratory finding was observed. AC-1370 showed a satisfactory clinical efficacy in treatment of the infections in the field of gynecology, and it has been concluded that AC-1370 will be an useful antibiotic for these infections.
对6例女性生殖器官感染患者进行了评估头孢咪唑(AC - 1370)有效性的临床研究。每天通过静脉滴注给予2克或4克AC - 1370,疗程为5至18天。2例患者疗效极佳,3例良好,1例子宫切除术后发生宫旁组织炎的患者疗效较差。有效率为83%。未观察到全身副作用或实验室检查异常。AC - 1370在妇科感染治疗中显示出令人满意的临床疗效,得出结论:AC - 1370将是治疗这些感染的一种有用抗生素。