Mure K, Yamashita K, Sengoku K, Shimizu T
Jpn J Antibiot. 1985 Apr;38(4):905-10.
Fundamental and clinical studies on cefpimizole (AC-1370), a new cephalosporin derivative, in the field of obstetrics and gynecology have been investigated, and the following results were obtained. High concentrations of AC-1370 in internal genital organs were detected after intravenous administration of 1.0 g of AC-1370. In the treatment of 14 cases of infection, the therapeutic effects were excellent or good in 11 cases and overall efficiency rate excluding 1 case with side effects was 84.6% (11/13). No serious side effect was observed except 1 case of nausea and vomiting.
对新型头孢菌素衍生物头孢米诺（AC-1370）在妇产科领域进行了基础和临床研究，获得了以下结果。静脉注射1.0g AC-1370后，在内生殖器器官中检测到高浓度的AC-1370。在治疗14例感染病例中，11例治疗效果为优或良，排除1例有副作用的病例后总有效率为84.6%（11/13）。除1例恶心呕吐外，未观察到严重副作用。
