Nakamura H, Nakamura J, Iwata Y, Hayashi S
Jpn J Antibiot. 1985 Apr;38(4):966-71.
Cefpimizole (AC-1370), a new cephalosporin antibiotic, was evaluated for its distribution in uterine tissue, penetration into retroperitoneal exudate and therapeutical effects on some infections in gynecology. The following results were obtained; The levels of AC-1370 in the cubital vein were similar to those in the uterine artery and this remained in the course of examinations after an 1 g intravenous injection. Seven patients with gynecological infections received AC-1370 by intravenous injection. The overall efficacy rate was 85.7%. No adverse reaction was observed in any of the cases treated with AC-1370, nor was there any marked changes in the laboratory findings.
头孢咪唑（AC - 1370）是一种新型头孢菌素抗生素，对其在子宫组织中的分布、向腹膜后渗出液中的渗透以及对某些妇科感染的治疗效果进行了评估。获得了以下结果：静脉注射1克后，在肘静脉中AC - 1370的水平与子宫动脉中的水平相似，并且在检查过程中一直保持这种状态。7例妇科感染患者接受了静脉注射AC - 1370治疗。总有效率为85.7%。在用AC - 1370治疗的任何病例中均未观察到不良反应，实验室检查结果也未出现任何明显变化。
