非洲猪瘟病毒在Vero细胞中复制对细胞核的需求。
Requirement of cell nucleus for African swine fever virus replication in Vero cells.
作者信息
Ortin J, Vińuela E
出版信息
J Virol. 1977 Mar;21(3):902-5. doi: 10.1128/JVI.21.3.902-905.1977.
Abstract
The role of the cell nucleus in the development of African swine fever virus in Vero cells has been studied. No viral growth could be detected in enucleated cells under conditions that allow normal development of Sindbis virus. Furthermore, African swine fever virus DNA synthesis was inhibited more than 95% after infection of enucleated Vero cells as compared with normal cells.
摘要
已对细胞核在非洲猪瘟病毒于非洲绿猴肾细胞（Vero细胞）中的发育过程中的作用进行了研究。在允许辛德毕斯病毒正常发育的条件下，去核细胞中未检测到病毒生长。此外，与正常细胞相比，去核的非洲绿猴肾细胞在感染后，非洲猪瘟病毒DNA合成被抑制了95%以上。
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