用于生命科学应用的基于卟啉的电纺纳米材料。

Porphyrin-based electrospun nanomaterials for life science applications.

作者信息

Mendes Ana C, Moura Nuno M M, Faustino M Amparo F, Neves M Graça P M S, Chronakis Ioannis S

机构信息

Research Group for Food Production Engineering, Laboratory of Nano-Bioscience, DTU-Food, Technical University of Denmark, Henrik Dams Allé B202, 2800 Kgs. Lyngby, Denmark.

LAQV-RQUIMTE, Department of Chemistry, University of Aveiro, Campus Universitário de Santiago, 3810-193 Aveiro, Portugal.

出版信息

BBA Adv. 2025 Apr 16;7:100160. doi: 10.1016/j.bbadva.2025.100160. eCollection 2025.

DOI:10.1016/j.bbadva.2025.100160

PMID:40337086

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12056381/

Abstract

Porphyrins are renowned for their utility in photocatalysis, electronics, sensors, solar cell dyes, and environmental remediation. However, their potential in life sciences applications remains underexplored, particularly in the context of encapsulation via electrospinning. This review examines recent advancements (2000-2025) in electrospinning techniques for encapsulating porphyrins, highlighting their unique properties, bioactivities, and versatile applications in life sciences. By combining the strengths of porphyrins and electrospinning technology, researchers can unlock transformative solutions for various life-science challenges, which include photodynamic therapy (PDT), composite materials for anti-microbial applications, sensors, and drug delivery. These efforts could push porphyrin-encapsulated materials from research concepts to applied societal solutions, addressing critical needs in healthcare and beyond to other fields.

摘要

卟啉因其在光催化、电子学、传感器、太阳能电池染料和环境修复等方面的应用而闻名。然而，它们在生命科学应用中的潜力仍未得到充分探索，特别是在通过静电纺丝进行封装的背景下。本综述考察了2000年至2025年期间用于封装卟啉的静电纺丝技术的最新进展，强调了它们的独特性质、生物活性以及在生命科学中的广泛应用。通过结合卟啉和静电纺丝技术的优势，研究人员可以为各种生命科学挑战找到变革性解决方案，包括光动力疗法（PDT）、用于抗菌应用的复合材料、传感器和药物递送。这些努力可能会将卟啉封装材料从研究概念推向实际社会解决方案，满足医疗保健及其他领域的关键需求。