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卢旺达孕妇个人接触细颗粒物、黑碳和一氧化碳的预测因素:HAPIN试验的基线数据

Predictors of Personal Exposure to Fine Particulate Matter, Black Carbon, and Carbon Monoxide among Pregnant Women in Rwanda: Baseline Data from the HAPIN Trial.

作者信息

Karakwende Patrick, Checkley William, Chen Yunyun, Clark Maggie L, Clasen Thomas, Dusabimana Ephrem, Jabbarzadeh Shirin, Johnson Michael, Kalisa Egide, Kirby Miles, Naher Luke, Ndagijimana Florien, Ndikubwimana Adolphe, Ntakirutimana Theoneste, Ntivuguruzwa Jean de Dieu, Peel Jennifer L, Piedrahita Ricardo, Pillarisetti Ajay, Rosa Ghislaine, Waller Lance A, Wang Jiantong, Young Bonnie N

机构信息

Department of Environmental Health, School of Public Health, University of Rwanda, Kigali, Rwanda.

Center for Global Non-Communicable Disease Research and Training, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.

出版信息

J Health Pollut. 2025 Jan 10;13(1-4):017001. doi: 10.1289/JHP1049. eCollection 2025 Dec.

Abstract

BACKGROUND

Exposure to household air pollution from the combustion of solid fuels is a leading risk factor for death and disease in low- and middle-income countries, where cleaner cooking and lighting options are often unavailable. Few studies have measured personal exposure during pregnancy, a sensitive period of development, particularly in Africa.

OBJECTIVE

We aimed to characterize exposure during early to midpregnancy among women in Rwanda and to assess predictors of personal exposure, including stove and fuel type, cooking behaviors, housing conditions, sociodemographic characteristics, and other potential sources of exposure.

METHODS

We assessed 24-h baseline personal exposure data among 798 pregnant women in the Household Air Pollution Intervention Network (HAPIN) trial in Rwanda, including 717 with fine particulate matter ( ), 569 with black carbon (BC), and 716 with carbon monoxide (CO) samples. Best subsets regression identified key predictors of personal , BC, and CO exposure, defined by maximizing adjusted values and minimizing prediction errors (Mallow's C and the Bayesian information criterion).

RESULTS

The 24-h median concentrations at baseline were [ ], ( 7.6), and ( 1.9) for BC, and CO, respectively. Households using kerosene as a primary lighting source had higher levels ( , 107) than those using electricity ( , 69). Women in households with modified biomass stoves with a chimney had lower median values ( , 52) for , compared with those in households using open fires ( , 74) and other traditional stove types ( , 43) that yielded the highest values. Consensus models from the best subsets' regression explained 26% of the variation in , 36% in BC, and 31% in CO concentrations.

CONCLUSIONS

Based on a unique and large dataset describing personal exposure among pregnant women in rural Rwanda, lighting and cooking practices described some variability in household concentrations, but overall, substantial unexplained variability remained. https://doi.org/10.1289/JHP1049.

摘要

背景

在低收入和中等收入国家,固体燃料燃烧产生的家庭空气污染是导致死亡和疾病的主要风险因素,而这些国家往往没有更清洁的烹饪和照明选择。很少有研究测量孕期(一个发育敏感期)的个人暴露情况,尤其是在非洲。

目的

我们旨在描述卢旺达妇女孕早期至孕中期的暴露特征,并评估个人暴露的预测因素,包括炉灶和燃料类型、烹饪行为、住房条件、社会人口学特征以及其他潜在暴露源。

方法

我们在卢旺达家庭空气污染干预网络(HAPIN)试验中评估了798名孕妇的24小时基线个人暴露数据,包括717名有细颗粒物( )样本的孕妇、569名有黑碳(BC)样本的孕妇和716名有一氧化碳(CO)样本的孕妇。最佳子集回归确定了个人 、BC和CO暴露的关键预测因素,其定义为最大化调整后的 值并最小化预测误差(马洛斯C统计量和贝叶斯信息准则)。

结果

基线时24小时中位数浓度分别为: 为 [ ], BC为 ( 7.6), CO为 ( 1.9)。以煤油作为主要照明源的家庭的 水平( , 107)高于使用电力的家庭( , 69)。与使用明火( , 74)和产生最高值的其他传统炉灶类型( , 43)的家庭相比,使用带烟囱的改良生物质炉灶的家庭中妇女的 中位数较低( , 52)。最佳子集回归的共识模型解释了 浓度变化的26%、BC浓度变化的36%和CO浓度变化的31%。

结论

基于描述卢旺达农村孕妇个人暴露情况的独特且庞大的数据集,照明和烹饪方式在家庭 浓度方面呈现出一定变异性,但总体而言,仍存在大量无法解释的变异性。https://doi.org/10.1289/JHP1049

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8a8/12061229/1aa18f32de91/jhp1049_f1.jpg

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