Gerards Marissa H G, Verburg Arie C, Slotegraaf Anne I, van Heerde Ron, de Bie Rob A, van der Wees Philip J, Lenssen Antoine F, Hoogeboom Thomas J
Department of Epidemiology, Care and Public Health Institute (CAPHRI), Faculty of Health, Medicine and Life Sciences, Maastricht University, 6229 HA Maastricht, Limburg, The Netherlands.
Academy for Physiotherapy, Zuyd University of Applied Sciences, 6411 RZ Heerlen, Limburg, The Netherlands.
Phys Ther. 2025 Jun 2;105(6). doi: 10.1093/ptj/pzaf065.
Current insight into recovery and real-world treatment of people with persistent complaints after SARS-CoV-2 infection is limited.
The objective of this study was to describe the content, duration, and reasons for initiating and terminating physical therapist interventions and (factors contributing to) changes in outcomes before and after treatment.
This was a prospective cohort study in Dutch primary care allied health care.
Participants were patients receiving allied health care treatment after SARS-CoV-2 infection.
The intervention was primary care physical therapy.
Self-reported functioning (patient-specific functional scale [PSFS]), 6-min walk test (6MWT), sit-to-stand performance (5 times sit-to-stand [5TSTS]), grip strength, and treatment characteristics were measured pre- and post-treatment. Associations between baseline characteristics, pre-treatment scores, and clinically important improvement on PSFS were calculated.
Nine hundred ninety-two patients (mean age 50 years [SD = 13]) were included. Median treatment duration was 24 weeks (IQR = 17-26) and 31 sessions (19-43). Most selected treatment goals were to improve endurance (74%) and physical functioning (72%). In 59% of treatment episodes, therapists reported that patients had achieved the main treatment goal. Mean change scores (95% CIs) were -4.1 points (-4.4 to -3.8) on the PSFS, 70 m (61-78) on the 6MWT, -3.0 s (-3.4 to -2.5) on the 5TSTS, and 3.0 kg (2.1-3.9) on grip strength. Females and participants with worse baseline scores on PSFS had greater odds of reporting a clinically important improvement on the PSFS. Patients with longer 5TSTS times had lower odds.
Most patients achieved their treatment goals and demonstrated clinically important improvements on PSFS and 6MWT. This study provides information on the most important therapeutic goals and provides estimates for realistic treatment episodes.
This article provides insight into real-world physical therapy in patients experiencing persistent complaints after SARS-CoV-2 infection. Additionally, insight into their recovery is provided, showing that patients improve significantly and clinically important on self-reported functioning, 6-min walk test, and sit-to-stand performance.
目前对于感染SARS-CoV-2后持续存在不适症状的患者的康复情况及实际治疗情况了解有限。
本研究的目的是描述物理治疗师干预措施的内容、持续时间以及开始和终止干预的原因，以及治疗前后结果变化的（促成）因素。
这是一项在荷兰初级保健联合医疗保健机构进行的前瞻性队列研究。
参与者为感染SARS-CoV-2后接受联合医疗保健治疗的患者。
干预措施为初级保健物理治疗。
在治疗前后测量自我报告的功能（患者特定功能量表[PSFS]）、6分钟步行试验（6MWT）、从坐到站的表现（5次从坐到站[5TSTS]）、握力以及治疗特征。计算基线特征、治疗前分数与PSFS上具有临床意义的改善之间的关联。
纳入了992名患者（平均年龄50岁[标准差=13]）。治疗持续时间的中位数为24周（四分位间距=17-26），治疗疗程为31次（19-43）。大多数选定的治疗目标是提高耐力（74%）和身体功能（72%）。在59%的治疗疗程中，治疗师报告患者实现了主要治疗目标。PSFS的平均变化分数（95%置信区间）为-4.1分（-4.4至-3.8），6MWT为70米（61-78），5TSTS为-3.0秒（-3.4至-2.5），握力为3.0千克（2.1-3.9）。女性和PSFS基线分数较差的参与者在PSFS上报告具有临床意义的改善的几率更高。5TSTS时间较长的患者几率较低。
大多数患者实现了他们的治疗目标，并在PSFS和6MWT上表现出具有临床意义的改善。本研究提供了关于最重要治疗目标的信息，并给出了实际治疗疗程的估计。
本文深入探讨了感染SARS-CoV-2后持续存在不适症状的患者的实际物理治疗情况。此外，还深入了解了他们的康复情况，表明患者在自我报告的功能、6分钟步行试验和从坐到站的表现方面有显著改善且具有临床意义。
