Ang Seng Bin, Sugianto Stella Rizalina Sasha, Tan Felicia Clara Jun Hui, Davison Sonia, Yu Qi, Terauchi Masakazu, Kim Mee-Ran, Shah Jignesh, Nasreen Shaikh Zinnat Ara, Ho Choon Moy, Sodnomdorj Enkhee, Siregar Muhammad Fidel Ganis, Hussain Rubina, Noblejas-Gamilla Ma Corazon Zaida, Chua Yang, Tsai Yung-Chieh, Jaisamrarn Unnop
Family Medicine Service, KK Women's and Children's Hospital, Singapore.
Department of Obstetrics and Gynaecology, KK Women's and Children's Hospital, Singapore.
J Menopausal Med. 2025 Apr;31(1):3-11. doi: 10.6118/jmm.25104.
This study aimed to achieve expert consensus on menopause management in the Asia-Pacific region, taking into account patient diversity, the latest evidence, and current treatment options.
A focused literature search was performed to identify clinical practice statements on menopause management. Menopause experts were nominated by members of the Asia-Pacific Menopause Federation (APMF) society. A modified Delphi methodology, involving iterative rounds of anonymous surveys, was employed until consensus was reached for each statement. Consensus was defined as ≥ 70% of experts voting 'agree' or 'strongly agree' for a given clinical practice statement.
A total of 39 participants from 14 different APMF member societies were involved. Eighty-five clinical practice statements reached a consensus. Based on the clinical practice statements, an algorithm was created as a tool to guide clinicians on menopause management. APMF experts agreed that, in addition to vasomotor symptoms, Asian women experiencing somatic or psychological symptoms may also benefit from treatment with menopausal hormone therapy (MHT). MHT should also be considered for the prevention of osteoporosis in asymptomatic peri- and postmenopausal women.
This APMF consensus statement supersedes the previous one published in 2008. It provides guidance to gynecologists, endocrinologists, family physicians, and other healthcare professionals in delivering optimal care to menopausal women in the ethnically and culturally diverse Asia-Pacific region.
本研究旨在就亚太地区绝经管理达成专家共识，同时考虑患者的多样性、最新证据及当前的治疗选择。
进行了针对性的文献检索，以确定有关绝经管理的临床实践声明。亚太绝经联合会（APMF）学会成员提名了绝经专家。采用一种改良的德尔菲方法，包括多轮匿名调查，直至就每项声明达成共识。共识的定义为，对于某一临床实践声明，≥70%的专家投票“同意”或“强烈同意”。
共有来自14个不同APMF成员学会的39名参与者参与。85条临床实践声明达成了共识。基于这些临床实践声明，创建了一种算法作为指导临床医生进行绝经管理的工具。APMF专家一致认为，除血管舒缩症状外，出现躯体或心理症状的亚洲女性也可能从绝经激素治疗（MHT）中获益。对于无症状的围绝经期和绝经后女性预防骨质疏松症，也应考虑使用MHT。
本APMF共识声明取代了2008年发表的上一份声明。它为妇科医生、内分泌科医生、家庭医生及其他医疗保健专业人员在为亚太地区种族和文化多样的绝经女性提供最佳护理方面提供了指导。
