Suthar Pokhraj P, Ansari Shehbaz M, Lotfian Golnaz, Abdel-Hadi Sarah, Dua Sumeet G
Department of Diagnostic Radiology and Nuclear Medicine, Rush University Medical Center, Chicago, USA.
Cureus. 2025 May 11;17(5):e83902. doi: 10.7759/cureus.83902. eCollection 2025 May.
Ventriculoperitoneal (VP) shunting is a critical intervention for managing hydrocephalus through cerebrospinal fluid (CSF) diversion. This report presents two rare and previously undocumented cases in which patients with long-standing VP shunts developed extensive dural fat accumulation, as evidenced by computed tomography (CT) and magnetic resonance imaging (MRI). These findings are highly suggestive of lipomatous dural metaplasia - a phenomenon that remains largely unaddressed in current medical literature. These cases are notable for their distinctive imaging features and the exclusion of alternative diagnoses, offering a compelling basis for further inquiry. By documenting these unique presentations, this manuscript aims to raise awareness and stimulate research into the pathophysiology, clinical implications, and diagnostic criteria of dural fat accumulation associated with chronic CSF shunting.
脑室腹腔(VP)分流术是通过脑脊液(CSF)引流来治疗脑积水的关键干预措施。本报告介绍了两例罕见且此前未记录的病例,长期进行VP分流术的患者出现了广泛的硬脑膜脂肪堆积,计算机断层扫描(CT)和磁共振成像(MRI)证实了这一点。这些发现高度提示为脂肪性硬脑膜化生——这一现象在当前医学文献中基本未被提及。这些病例因其独特的影像学特征以及排除了其他诊断而值得关注,为进一步研究提供了有力依据。通过记录这些独特表现,本手稿旨在提高对与慢性CSF分流相关的硬脑膜脂肪堆积的病理生理学、临床意义和诊断标准的认识,并激发相关研究。