Sommers A A
Schizophr Bull. 1985;11(3):364-79. doi: 10.1093/schbul/11.3.364.
Research into the so-called negative symptoms of schizophrenia is plagued by often ignored problems in item identification, scale selection, quantification, clinical assessment process, and symptom (and, probably, causal) nonspecificity. Neither a negative symptom syndrome per se nor the recent rating scales designed to measure it have been validated, although some data useful in this regard have been presented for the scales. Since no criterion against which to validate these scales exists, construct validation is needed. The construct of negative symptoms, as defined by its hypothesized empirical relationships with other variables, and the procedures used to measure it must be validated simultaneously and gradually through a programmatic series of studies. In the meantime, research results pertaining to negative symptoms should be interpreted with considerable caution.
对精神分裂症所谓阴性症状的研究受到诸多常被忽视的问题困扰，这些问题涉及条目识别、量表选择、量化、临床评估过程以及症状（可能还有病因）的非特异性。阴性症状综合征本身以及最近设计用于测量它的评定量表均未得到验证，尽管已针对这些量表呈现了一些这方面有用的数据。由于不存在用于验证这些量表的标准，因此需要进行结构效度验证。阴性症状的结构，由其与其他变量的假设实证关系所定义，以及用于测量它的程序，必须通过一系列有计划的研究同时且逐步地进行验证。与此同时，与阴性症状相关的研究结果在解释时应极为谨慎。
