Sawczuk Beata, Nayar Suresh, Szutko Paweł, Sierpińska Teresa
Department of Prosthodontics, Medical University of Białystok, ul Kilińskiego 1, 15-089 Białystok, Poland.
Institute for Reconstructive Sciences in Medicine, University of Alberta, 1W-02, 16940 87 Ave NW, Edmonton, AB T5R 4A3, Canada.
Nutrients. 2025 Apr 28;17(9):1483. doi: 10.3390/nu17091483.
Head and neck cancers (HNCs) and their surgical treatment can result in significant functional deficits including impaired masticatory function, dysphagia and dysgeusia, among others. These contribute to nutritional deficits weakening immune responses, increased post-surgical infections and complications.
This study assesses the impact of removable prosthetic restorations on nutritional habits in edentulous patients who have undergone surgery for head and neck cancer.
This study included 44 post-surgical oncology patients and 20 healthy edentulous patients who served as controls. All patients received removable acrylic complete prostheses. Controls received maxillary and mandibular complete prostheses and HNC patients received post-resection complete maxillary and mandibular prostheses. Nutritional intake was assessed through a 24 h dietary recall and the Food Frequency Questionnaire administered before prosthetic treatment and 6 weeks and 3, 6 and 12 months after the provision of removable prosthetic restorations.
This study found that both patient groups maintained consistent meal frequency, with the study group exhibiting stable food intake over time. The intake of various food items fluctuated post prosthesis delivery in both groups, with an initial decline followed by partial recovery. Statistically significant differences were observed in food preferences; however, diet variations between and within the groups were not statistically significant.
This study found that the use of removable prosthetic restoration in surgically managed edentulous head and neck cancer patients and edentulous controls showed no significant differences apart from certain food preferences and diet variations. A prolonged adaptation period was observed highlighting the need to include clinical dietitians to support the patients.
头颈癌（HNCs）及其外科治疗可导致显著的功能缺陷，包括咀嚼功能受损、吞咽困难和味觉障碍等。这些会导致营养缺乏，削弱免疫反应，增加术后感染和并发症。
本研究评估可摘义齿修复对接受过头颈癌手术的无牙患者营养习惯的影响。
本研究纳入44例外科肿瘤患者和20例健康无牙患者作为对照。所有患者均接受可摘丙烯酸全口义齿。对照组接受上颌和下颌全口义齿，头颈癌患者接受切除术后上颌和下颌全口义齿。通过24小时饮食回顾和食物频率问卷评估营养摄入情况，在义齿治疗前以及提供可摘义齿修复后6周、3个月、6个月和12个月进行。
本研究发现两组患者的进餐频率均保持一致，研究组患者的食物摄入量随时间推移保持稳定。两组患者在义齿佩戴后各种食物的摄入量均有波动，最初下降，随后部分恢复。在食物偏好方面观察到统计学上的显著差异；然而，组间和组内的饮食差异无统计学意义。
本研究发现，在接受手术治疗的无牙头颈癌患者和无牙对照患者中使用可摘义齿修复，除了某些食物偏好和饮食差异外，没有显著差异。观察到适应期较长，这突出表明需要有临床营养师来支持患者。
