Wilpizeski C R, Lowry L D, Eyyunni U, el Raheb M, Goldman W S
Am J Otolaryngol. 1985 Jul-Aug;6(4):258-63. doi: 10.1016/s0196-0709(85)80052-1.
Adult male squirrel monkeys were the subjects of experiments conducted to determine whether or not repeated exposures to sickness-inducing horizontal rotation would result in behavioral conditioning of emetic responses. The development of conditioned food aversion and feeding suppression as a consequence of pre- and postrotation eating was quantified. It was concluded that neither instrumental conditioning nor classical conditioning were valid alternative hypotheses for the occurrence of repeated vomiting episodes over a period of ten daily exposures to motion. Conditioned aversion to fresh banana and feeding suppression developed gradually if rotation, which induced multiple bouts of vomiting, was sustained for 1- or 2-hour sessions. If spinning was terminated immediately after the first emetic response, no aversion or suppression emerged. The occurrence of food aversion, by itself, is questioned as a valid index of the presence of subjective concomitants of motion sickness in animals.
成年雄性松鼠猴是实验对象，这些实验旨在确定反复暴露于导致疾病的水平旋转是否会导致催吐反应的行为条件反射。对旋转前后进食导致的条件性食物厌恶和进食抑制的发展进行了量化。得出的结论是，在每天暴露于运动十次的时间段内，反复呕吐发作的发生，工具性条件反射和经典条件反射都不是有效的替代假设。如果诱导多次呕吐发作的旋转持续1或2小时，对新鲜香蕉的条件性厌恶和进食抑制会逐渐形成。如果在第一次催吐反应后立即停止旋转，则不会出现厌恶或抑制。食物厌恶的出现本身是否作为动物晕动病主观伴随症状存在的有效指标受到质疑。
