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Opportunities for microbiome-based therapeutics in preterm infants.

作者信息

Wroot Emily, Chapman Jonathan A, Young Gregory R, Berrington Janet E, Stewart Christopher J

机构信息

Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.

Newcastle Neonatal Service, Newcastle Hospitals NHS Trust, Newcastle upon Tyne, UK.

出版信息

Nat Microbiol. 2025 May 16. doi: 10.1038/s41564-025-02010-x.

DOI:10.1038/s41564-025-02010-x
PMID:40379933
Abstract
摘要

相似文献

1
Opportunities for microbiome-based therapeutics in preterm infants.基于微生物群的早产儿治疗方法的机遇。
Nat Microbiol. 2025 May 16. doi: 10.1038/s41564-025-02010-x.
2
Antimicrobial Peptides (AMPs) and the Microbiome in Preterm Infants: Consequences and Opportunities for Future Therapeutics.抗菌肽 (AMPs) 和早产儿微生物组：未来治疗的后果和机遇。
Int J Mol Sci. 2024 Jun 18;25(12):6684. doi: 10.3390/ijms25126684.
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Influence of maternal breast milk ingestion on acquisition of the intestinal microbiome in preterm infants.母乳摄入对早产儿肠道微生物组获得的影响。
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4
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Free Radic Biol Med. 2019 Oct;142:146-154. doi: 10.1016/j.freeradbiomed.2019.02.032. Epub 2019 Mar 6.
5
Postnatal age is strongly correlated with the early development of the gut microbiome in preterm infants.产后年龄与早产儿肠道微生物群的早期发育密切相关。
Transl Pediatr. 2021 Sep;10(9):2313-2324. doi: 10.21037/tp-21-367.
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A Scoping Review of the Oral Microbiome in Preterm Infants.早产儿口腔微生物组的范围综述。
Am J Perinatol. 2024 May;41(S 01):e2990-e3002. doi: 10.1055/s-0043-1776344. Epub 2023 Oct 31.
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: Host-Microbiome Interaction and Mechanism of Action in Preventing Common Gut-Microbiota-Associated Complications in Preterm Infants: A Narrative Review.宿主-微生物群相互作用及预防早产儿常见肠道微生物群相关并发症的作用机制：叙述性综述。
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Adv Biol (Weinh). 2022 Aug;6(8):e2101313. doi: 10.1002/adbi.202101313. Epub 2022 Jun 1.
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Reversible aberrancies in gut microbiome of moderate and late preterm infants: results from a randomized, controlled trial.中重度早产儿肠道微生物组可逆性紊乱：一项随机对照试验的结果。
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Intestinal dysbiosis in preterm infants preceding necrotizing enterocolitis: a systematic review and meta-analysis.早产儿坏死性小肠结肠炎发病前肠道菌群失调：系统评价和荟萃分析。
Microbiome. 2017 Mar 9;5(1):31. doi: 10.1186/s40168-017-0248-8.

本文引用的文献

1
Reevaluating the FDA's warning against the use of probiotics in preterm neonates: A societal statement by ESPGHAN and EFCNI.重新评估 FDA 对早产儿使用益生菌的警告：ESPGHAN 和 EFCNI 的社会声明。
J Pediatr Gastroenterol Nutr. 2024 Jun;78(6):1403-1408. doi: 10.1002/jpn3.12204. Epub 2024 Apr 4.
2
Probiotics, Prebiotics, Lactoferrin, and Combination Products for Prevention of Mortality and Morbidity in Preterm Infants: A Systematic Review and Network Meta-Analysis.益生菌、益生元、乳铁蛋白及联合制剂预防早产儿病死率和发病的系统评价和网络荟萃分析。
JAMA Pediatr. 2023 Nov 1;177(11):1158-1167. doi: 10.1001/jamapediatrics.2023.3849.
3
Probiotics to prevent necrotising enterocolitis in very preterm or very low birth weight infants.
益生菌预防极早产儿或极低出生体重儿坏死性小肠结肠炎。
Cochrane Database Syst Rev. 2023 Jul 26;7(7):CD005496. doi: 10.1002/14651858.CD005496.pub6.
4
Particular genomic and virulence traits associated with preterm infant-derived toxigenic Clostridium perfringens strains.与早产婴儿来源的产毒梭状芽孢杆菌相关的特定基因组和毒力特征。
Nat Microbiol. 2023 Jun;8(6):1160-1175. doi: 10.1038/s41564-023-01385-z. Epub 2023 May 25.
5
Late-Onset Sepsis Among Very Preterm Infants.极早产儿晚发型败血症。
Pediatrics. 2022 Dec 1;150(6). doi: 10.1542/peds.2022-058813.
6
Infant Formula With a Specific Blend of Five Human Milk Oligosaccharides Drives the Gut Microbiota Development and Improves Gut Maturation Markers: A Randomized Controlled Trial.含五种人乳低聚糖特定组合的婴儿配方奶粉促进肠道微生物群发育并改善肠道成熟标志物：一项随机对照试验。
Front Nutr. 2022 Jul 6;9:920362. doi: 10.3389/fnut.2022.920362. eCollection 2022.
7
Fecal filtrate transplantation protects against necrotizing enterocolitis.粪便滤液移植可预防坏死性小肠结肠炎。
ISME J. 2022 Mar;16(3):686-694. doi: 10.1038/s41396-021-01107-5. Epub 2021 Sep 22.
8
Postbiotic Supplementation for Children and Newborn's Health.后生元补充剂对儿童和新生儿健康的影响。
Nutrients. 2021 Feb 27;13(3):781. doi: 10.3390/nu13030781.
9
Human milk oligosaccharide DSLNT and gut microbiome in preterm infants predicts necrotising enterocolitis.人乳寡糖 DSLNT 和早产儿肠道微生物群可预测坏死性小肠结肠炎。
Gut. 2021 Dec;70(12):2273-2282. doi: 10.1136/gutjnl-2020-322771. Epub 2020 Dec 16.
10
Maternal Fecal Microbiota Transplantation in Cesarean-Born Infants Rapidly Restores Normal Gut Microbial Development: A Proof-of-Concept Study.剖宫产儿的母体粪便微生物移植可快速恢复正常肠道微生物发育：概念验证研究。
Cell. 2020 Oct 15;183(2):324-334.e5. doi: 10.1016/j.cell.2020.08.047. Epub 2020 Oct 1.