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Progress to Date on Cranial Electromagnetic Field Stimulation to Modulate Brain Activity.

作者信息

Wang Alice S, Savla Paras, Brazdzionis James, Ko Katherine, Miulli Dan E

机构信息

Neurosurgery, Riverside University Health System Medical Center, Moreno Valley, USA.

Neurosurgery, Arrowhead Regional Medical Center, Colton, USA.

出版信息

Cureus. 2025 May 22;17(5):e84653. doi: 10.7759/cureus.84653. eCollection 2025 May.


DOI:10.7759/cureus.84653
PMID:40416912
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12101138/
Abstract

BACKGROUND: The electromagnetic field (EMF) of the brain can be modulated through EMF stimulation. The authors investigate whether longer duration of continuous EMF stimulation using a novel method to identify and provide feedback and adjustment of EMF recording would translate into sustained improvement in EMF patterns, such as higher amplitude with correlating improvement in clinical symptoms or deficits. METHODS: From January 2025 to February 2025, a prospective study enrolled patients greater than 18 years old diagnosed with atraumatic and traumatic brain injury who underwent EMF stimulation within 24 hours of presentation. EMF data were collected using DAQami software (Dataq Instruments, Akron, Ohio) and analyzed using fast Fourier transformation (FFT) with Igor Pro 8 software (Wavemetrics Inc., Lake Oswego, Oregon). Based on each patient's clinical presentations and/or radiographic findings, localization of brain injuries, frequency selection, and optimal voltage stimulation were determined in real-time followed by delivery of incremental increase in duration of stimulation from 3, 5, 8, and 10 minutes until improvement in clinical symptoms and/or neurological deficits and sustained EMF change was achieved. RESULTS: Ten patients were included in this study, with a mean age of 47.1 years. Mechanisms of injury included spontaneous hypertensive intracranial hemorrhage (1 patient) and head trauma after motor vehicle collision, dirt bike accident, and ground-level fall (9 patients). Radiographic findings included spontaneous basal ganglia hemorrhage (1 patient), isolated traumatic subdural hematoma (1 patient), traumatic subarachnoid hemorrhage (1 patient), and no intracranial abnormalities (7 patients). Clinical resolution of their neurological symptoms or remaining asymptomatic was achieved in five patients after three minutes of continuous EMF stimulation, two patients after five minutes of continuous EMF stimulation, and one patient after 10 minutes of continuous EMF stimulation (Table 1). Patient 8 declined to continue with the study after three minutes of continuous EMF stimulation, and patient 9 declined to continue with the study after five minutes of continuous EMF stimulation. CONCLUSIONS: This study reveals the progress made to date utilizing a novel technology of EMF measurement at a distance, in real-time, using the non-invasive, lightweight portable helmet, and continuous feedback. The range of brain EMF can be stimulated at the optimal frequency and voltage with or without longer duration of stimulation in a precise and prescribed manner to produce sustained genetic and neuronal changes to improve, recover, and enhance the brain function in a sample of patients with atraumatic and traumatic brain injury and improve or resolve their neurological symptoms or deficits. It illustrates the necessity of real-time evaluation and adjustment of brain EMF for EMF stimulation. It further indicates the efficacy of tailored and precise EMF stimulation to the specific patient, the specific area of abnormality, and for a specific pathology studied. The range of unique EMF corresponds to macroscopic and microscopic functions, the vast majority of which have yet to be qualified and quantified, and for which most brain diseases have yet to be studied.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4876/12101138/497c26cd602e/cureus-0017-00000084653-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4876/12101138/9666cbbc0b28/cureus-0017-00000084653-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4876/12101138/860a9bb4e429/cureus-0017-00000084653-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4876/12101138/497c26cd602e/cureus-0017-00000084653-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4876/12101138/9666cbbc0b28/cureus-0017-00000084653-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4876/12101138/860a9bb4e429/cureus-0017-00000084653-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4876/12101138/497c26cd602e/cureus-0017-00000084653-i03.jpg

相似文献

[1]
Progress to Date on Cranial Electromagnetic Field Stimulation to Modulate Brain Activity.

Cureus. 2025-5-22

[2]
Optimal Voltage for Cranial Electromagnetic Field Stimulation to Modulate Brain Activity.

Cureus. 2025-4-10

[3]
Localization of Brain Injuries Using Cranial Electromagnetic Fields.

Cureus. 2025-3-13

[4]
Optimal Frequency for Cranial Electromagnetic Field Stimulation.

Cureus. 2025-3-29

[5]
A Swine Model of Traumatic Brain Injury: Effects of Neuronally Generated Electromagnetic Fields and Electromagnetic Field Stimulation on Traumatic Brain Injury-Related Changes.

Cureus. 2023-7-27

[6]
A Swine Model of Neural Circuit Electromagnetic Fields: Effects of Immediate Electromagnetic Field Stimulation on Cortical Injury.

Cureus. 2023-8-19

[7]
The Use of Induction Sensors and Helmet-Based Shielding Technology to Identify Differences in Electromagnetic Fields in Patients With Cranial Neurological Disease Versus Healthy Controls.

Cureus. 2023-9-16

[8]
A Swine Model of Changes in the Neuronal Electromagnetic Field After Traumatic Brain Injury: A Pilot Study.

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[9]
Vesicoureteral Reflux

2025-1

[10]
Measuring the Electromagnetic Field of the Human Brain at a Distance Using a Shielded Electromagnetic Field Channel.

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本文引用的文献

[1]
Optimal Voltage for Cranial Electromagnetic Field Stimulation to Modulate Brain Activity.

Cureus. 2025-4-10

[2]
Optimal Frequency for Cranial Electromagnetic Field Stimulation.

Cureus. 2025-3-29

[3]
Localization of Brain Injuries Using Cranial Electromagnetic Fields.

Cureus. 2025-3-13

[4]
Effect of Electromagnetic Field on Proliferation and Migration of Fibroblasts and Keratinocytes: Implications in Wound Healing and Regeneration.

J Biotechnol Biomed. 2024

[5]
Transcriptional and Translational Regulation of Differentially Expressed Genes in Yucatan Miniswine Brain Tissues following Traumatic Brain Injury.

J Bioinform Syst Biol. 2024

[6]
Epidemiology, Pathophysiology, and Treatment Strategies of Concussions: A Comprehensive Review.

Fortune J Health Sci. 2024

[7]
Transcriptomic Analysis of Gene Expression and Effect of Electromagnetic Field in Brain Tissue after Traumatic Brain Injury.

J Biotechnol Biomed. 2024

[8]
Modulation of Inflammatory Response by Electromagnetic Field Stimulation in Traumatic Brain Injury in Yucatan Swine.

J Surg Res (Houst). 2024

[9]
The Use of Induction Sensors and Helmet-Based Shielding Technology to Identify Differences in Electromagnetic Fields in Patients With Cranial Neurological Disease Versus Healthy Controls.

Cureus. 2023-9-16

[10]
A Swine Model of Neural Circuit Electromagnetic Fields: Effects of Immediate Electromagnetic Field Stimulation on Cortical Injury.

Cureus. 2023-8-19

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